{"product_id":"a-practical-guide-to-assay-taosheng-chen-9781420070507","title":"A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery","description":"\u003cp\u003eThe development of suitable assays, the integration of appropriate technology, and the effective management of the essential infrastructure are all critical to the success of any high-throughput screening (HTS) endeavor. However, few scientists have the multidisciplinary experience needed to control all aspects of an HTS drug discovery project. \u003cstrong\u003eA Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery\u003c\/strong\u003e integrates the experience of diverse experts who offer fundamental and practical guidance across numerous situations.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eThe book first discusses assay developments for important target classes such as protein kinases and phosphatases, proteases, nuclear receptors, G protein-coupled receptors, ion channels, and heat shock proteins. It next examines assay developments for cell viability, apoptosis, and infectious diseases. The contributors explore the application of emerging technologies and systems, including image-based high content screening, RNA interference, and primary cells. Finally, they discuss the essential components of the integrated HTS process, such as screening automation, compound library management, the screening of natural products from botanical sources, and screening informatics.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eDesigned to motivate researchers to bring further advances to the field, this volume provides practical guidance on how to initiate, validate, optimize, and manage a bioassay intended to screen large collections of compounds. Drawing on the knowledge from experts actively involved in assay development and HTS, this is a resource that is both comprehensive and focused. \u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Taosheng Chen\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1420070509\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781420070507\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e CRC Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 12\/01\/2009\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 292\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.55lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.00w x 0.80d\u003cbr\u003e\u003cbr\u003e\u003cb\u003eReview Citation(s): \u003c\/b\u003e\u003cbr\u003e\u003ci\u003eScitech Book News\u003c\/i\u003e 06\/01\/2010 pg. 121","brand":"Taosheng Chen","offers":[{"title":"Hardcover","offer_id":48113499865343,"sku":"9781420070507","price":270.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_ba4e07f1-964a-423c-be96-066562a8589b.jpg?v=1769615431","url":"https:\/\/www.whiterainbookhouse.com\/products\/a-practical-guide-to-assay-taosheng-chen-9781420070507","provider":"WR Book House","version":"1.0","type":"link"}