{"product_id":"adme-and-translational-pharmacokinetics-honghui-zhou-9781118898642","title":"Adme and Translational Pharmacokinetics \/ Pharmacodynamics of Therapeutic Proteins: Applications in Drug Discovery and Development","description":"\u003cp\u003e\u003cb\u003eWith an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs.\u003c\/b\u003e\u003c\/p\u003e \u003cul\u003e \u003cli\u003eDetails cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic \/ pharmacodynamics) modeling for biologic drugs\u003c\/li\u003e \u003cli\u003eCombines theoretical with practical aspects of ADME in biologic drug discovery and development and compares innovator biologics with biosimilar biologics and small molecules with biologics, giving a lessons-learned perspective\u003c\/li\u003e \u003cli\u003eIncludes case studies about leveraging ADME to improve biologics drug development for monoclonal antibodies, fusion proteins, pegylated proteins, ADCs, bispecifics, and vaccines\u003c\/li\u003e \u003cli\u003ePresents regulatory expectations and industry perspectives for developing biologic drugs in USA, EU, and Japan\u003c\/li\u003e \u003cli\u003eProvides mechanistic insight into biodistribution and target-driven pharmacokinetics in important sites of action such as tumors and the brain\u003c\/li\u003e \u003c\/ul\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Honghui Zhou,Frank-Peter Theil\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1118898648\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781118898642\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Wiley\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 11\/23\/2015\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 480\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 3.50lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 11.20h x 8.70w x 1.00d","brand":"Honghui Zhou","offers":[{"title":"Hardcover","offer_id":49082694861055,"sku":"9781118898642","price":165.95,"currency_code":"USD","in_stock":false}],"url":"https:\/\/www.whiterainbookhouse.com\/products\/adme-and-translational-pharmacokinetics-honghui-zhou-9781118898642","provider":"WR Book House","version":"1.0","type":"link"}