{"product_id":"animal-and-translational-models-for-robert-a-mcarthur-9780123738608","title":"Animal and Translational Models for CNS Drug Discovery: Reward Deficit Disorders","description":"\u003cp\u003e\u003ci\u003eReward Deficit Disorders\u003c\/i\u003e is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for reward deficit disorders such as alcohol dependence, nicotine dependence, heroin and cocaine addiction, obesity, and gambling and impulse control disorders. \u003ci\u003eReward Deficit Disorders \u003c\/i\u003ehas introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. \u003ci\u003eReward Deficit Disorders\u003c\/i\u003e also has a section dedicated to the specifics of the regulatory aspects to abuse liability testing. The aim of this series of volumes on \u003ci\u003eAnimal and Translational Models for CNS Drug Discovery\u003c\/i\u003e is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery.\u003c\/p\u003e \u003cp\u003eThis is the third volume in the three volume-set, \u003ci\u003eAnimal and Translational Models for CNS Drug Discovery\u003c\/i\u003e 978-0-12-373861-5, which is also available for purchase individually.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Robert A. McArthur\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0123738601\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780123738608\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Academic Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 10\/06\/2008\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 432\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 2.15lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.20h x 7.30w x 1.10d","brand":"Robert A. McArthur","offers":[{"title":"Hardcover","offer_id":47135220826367,"sku":"9780123738608","price":103.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_f6ed55c5-98a2-4274-98e5-11abaffb47c0.jpg?v=1755009491","url":"https:\/\/www.whiterainbookhouse.com\/products\/animal-and-translational-models-for-robert-a-mcarthur-9780123738608","provider":"WR Book House","version":"1.0","type":"link"}