{"product_id":"antiinflammatory-effect-of-prednisolone-ethoniosome-passent-gaafar-9783659565472","title":"Antiinflammatory Effect of Prednisolone Ethoniosome\u0026 Marketed Products","description":"Ethoniosomes (EVs) composed of span 60: CH (7:3) containing 20% (v\/v) ethanol and prepared by TFH method was prepared and tested for its irritation potential to the ocular tissue and its in vivo anti-inflammatory activity compared to commercial products. Also, the duration of action of the prepared EVs was determined. In addition to, measurement of the cumulative increase in the IOP for both; the prepared EVs and the conventional formulations. The results showed that, no signs of irritation were observed for either the cornea or the conjunctiva. The ocular anti-inflammatory activity of EVs entrapping Pred A and Pred P was significantly higher compared to conventional formulations. The cumulative IOP of TFH-EVs entrapping either Pred A or Pred P showed smaller increase in IOP compared to conventional formulations. Further, an obviously prolonged absorption and relatively slower elimination rates were demonstrated for Pred A EVs, Pred P EVs formulations. In conclusion, EVs may serve as a novel delivery system improving the ultimate outcome any drug can offer; which is high efficacy in terms of activity and duration of action and a lesser side effects in terms of IOP raising potentia\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Passent Gaafar, Ragwa Farid, Ossama Abdallah\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 3659565474\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9783659565472\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e LAP Lambert Academic Publishing\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 07\/09\/2014\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 60\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 0.22lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.00h x 6.00w x 0.14d","brand":"Passent Gaafar","offers":[{"title":"Paperback","offer_id":44201975578879,"sku":"9783659565472","price":43.09,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_e32b2ba9-f686-48fb-92ad-d81bf0f98b69.jpg?v=1691492509","url":"https:\/\/www.whiterainbookhouse.com\/products\/antiinflammatory-effect-of-prednisolone-ethoniosome-passent-gaafar-9783659565472","provider":"WR Book House","version":"1.0","type":"link"}