{"product_id":"application-of-the-difference-map-ivan-rankenburg-9783836471060","title":"Application of the Difference Map Algorithm to Protein Structure Prediction","description":"A powerful new search algorithm, the difference map, has had notable success in many fields that involve finding a characteristic point in a high dimensional search space. The algorithm was first applied to a toy model of proteins in 2004. In that context, the difference map was able to find low energy \"folds\" better than any contemporary search algorithm. In this work, the same algorithm is applied to a realistic protein model. Though the algorithm finds low energy folds for the protein molecule, the energy function used is found to be inadequate to make the lowest energy state of the protein molecule the native conformation. In this work, the algorithm is described, and some example applications are given. Finally, the complete programming implementation of the algorithm to the problem of protein energy minimization is supplied.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Ivan Rankenburg\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 383647106X\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9783836471060\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e VDM Verlag Dr. Mueller E.K.\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 02\/28\/2008\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 204\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 0.73lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.61h x 6.69w x 0.43d","brand":"Ivan Rankenburg","offers":[{"title":"Paperback","offer_id":47305557213439,"sku":"9783836471060","price":85.32,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_29c23dc2-d98b-486c-97c9-3aff5dc6bc4e.jpg?v=1758831212","url":"https:\/\/www.whiterainbookhouse.com\/products\/application-of-the-difference-map-ivan-rankenburg-9783836471060","provider":"WR Book House","version":"1.0","type":"link"}