{"product_id":"autophagy-in-mammalian-systems-part-daniel-klionsky-9780123745477","title":"Autophagy in Mammalian Systems, Part B: Volume 452","description":"This is the companion volume to Daniel Klionsky's \u003ci\u003eAutophagy: Lower Eukaryotes, \u003c\/i\u003e which features the basic methods in autophagy covering yeasts and alternative fungi (aspergillus, podospora, magnaporthe). Klionsky is one of the leading authorities in the field. He is the editor-in-chief of \u003ci\u003eAutophagy.\u003c\/i\u003e The November 2007 issue of \u003ci\u003eNature Reviews\u003c\/i\u003e highlighted his article, \"Autophagy: From phenomenology to molecular understanding in less than a decade.\" He is currently editing guidelines for the field, with 230 contributing authors, that will publish in \u003ci\u003eAutophagy.\u003c\/i\u003e \u003cp\u003e\u003c\/p\u003eParticularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal \"house cleaning\" in the cell is called autophagy - literally self-eating. Breakthroughs in understanding the molecular basis of autophagy came after the cloning of ATG1 (autophagy-related gene 1) in yeast. (To date, 30 additional yeast genes have been identified.) These ATG genes in yeast were the stepping stones to the explosion of research into the molecular analysis of autophagy in higher eukaryotes. In the future, this research will help to design clinical approaches that can turn on autophagy and halt tumor growth.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Daniel Klionsky\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0123745470\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780123745477\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Academic Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 02\/01\/2009\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 560\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 2.24lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.00h x 6.20w x 1.30d","brand":"Daniel Klionsky","offers":[{"title":"Hardcover","offer_id":48112818684159,"sku":"9780123745477","price":225.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_26b0e70f-c985-4e75-83a4-5da7cee3dfb8.jpg?v=1769611153","url":"https:\/\/www.whiterainbookhouse.com\/products\/autophagy-in-mammalian-systems-part-daniel-klionsky-9780123745477","provider":"WR Book House","version":"1.0","type":"link"}