{"product_id":"autophagy-m-a-hayat-9780124055292","title":"Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging: Volume 3 - Role in Specific Diseases","description":"\u003cp\u003eUnderstanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and up-to-date, this book offers a valuable guide to these cellular processes whilst encouraging researchers to explore their potentially important connections. \u003c\/p\u003e \u003cp\u003eVolume 3 explores the role of autophagy in specific diseases and developments, including: Crohn's Disease, Gaucher Disease, Huntington's Disease, HCV infection, osteoarthritis, and liver injury. A full section is devoted to in-depth exploration of autophagy in tumor development and cancer. Finally, the work explores the relationship between autophagy and apoptosis, with attention to the ways in which autophagy regulates apoptosis, and the ways in which autophagy has been explored in Lepidoptera, elucidating the use of larval midgut as a model for such exploration. From these well-developed foundations, researchers, translational scientists, and practitioners may work to better implement more effective therapies against some of the most devastating human diseases.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eVolumes in the Series\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eVolume 1: Molecular Mechanisms.\u003c\/b\u003e Elucidates autophagy's association with numerous biological processes, including cellular development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. \u003cb\u003eVolume 2: Role in General Diseases.\u003c\/b\u003e Describes the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general diseases. \u003cb\u003eVolume 3: Role in Specific Diseases.\u003c\/b\u003e Explores the role of autophagy in specific diseases and developments, including: Crohn's Disease, Gaucher Disease, Huntington's Disease, HCV infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor development and cancer, as well as the relationship between autophagy and apoptosis.\u003cb\u003eVolume 4: Mitophagy.\u003c\/b\u003e Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson Disease, cardiac aging, and skeletal muscle atrophy. \u003cb\u003eVolume 5: Role in Human Diseases.\u003c\/b\u003e Comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer; and the duality of autophagy's effects in various cardiovascular, metabolic, and neurodegenerative disorders.\u003cb\u003eVolume 6: Regulation of Autophagy and Selective Autophagy.\u003c\/b\u003e Provides coverage of the mechanisms of regulation of autophagy; intracellular pathogen use of the autophagy mechanism; the role of autophagy in host immunity; and selective autophagy. \u003cb\u003eVolume 7: Role of Autophagy in Therapeutic Applications.\u003c\/b\u003e Provides coverage of the latest developments in autophagosome biogenesis and regulation; the role of autophagy in protein quality control; the role of autophagy in apoptosis; autophagy in the cardiovascular system; and the relationships between autophagy and lifestyle. \u003cb\u003eVolume 8: Autophagy and Human Diseases.\u003c\/b\u003e Reviews recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, and introduces new, more effective therapeutic strategies, in the development of targeted drugs and programmed cell death, providing information that will aid on preventing detrimental inflammation.\u003cb\u003eVolume 9: Necrosis and Inflammation in Human Diseases.\u003c\/b\u003e Emphasizes the role of Autophagy in necrosis and inflammation, explaining in detail the molecular mechanism(s) underlying the formation of autophagosomes, including the progression of Omegasomes to autophagosomes.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e M. A. Hayat\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 012405529X\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780124055292\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Academic Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 01\/31\/2014\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 432\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover","brand":"M. A. Hayat","offers":[{"title":"Hardcover","offer_id":48112828743935,"sku":"9780124055292","price":200.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_d9e7c992-25e3-4f92-8e2e-b998a8777a58.jpg?v=1769611214","url":"https:\/\/www.whiterainbookhouse.com\/products\/autophagy-m-a-hayat-9780124055292","provider":"WR Book House","version":"1.0","type":"link"}