{"product_id":"autophagy-m-a-hayat-9780128010327","title":"Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging: Volume 6- Regulation of Autophagy and Selective Autophagy","description":"\u003cp\u003eVolume 6 provides coverage of the mechanisms of regulation of autophagy; intracellular pathogen use of the autophagy mechanism; the role of autophagy in host immunity; and selective autophagy. Attention is given to a number of mechanistic advances in the understanding of regulation, particularly the importance of nutrient availability; microRNAs; and cross-talk with other protein degradation pathways. Intracellular pathogen repurposing of autophagy for pathogenic benefit is also provided, with coverage of Herpesvirus protein modulation of autophagy; the varicella-zoster virus and the maintenance of homeostasis; and the relationship between autophagy and the hepatitis b virus. \u003c\/p\u003e \u003cp\u003eThe significance of autophagy in host defense is elucidated, providing a specific focus on facilitation of antigen presentation; participation in thymic development; and the sharing of regulatory nodes with innate immunity. Selective autophagy for the degradation of mitochondria and endocytosed gap junctions are also explored. \u003c\/p\u003e \u003cp\u003eThis book is an asset to newcomers as a concise overview of the regulation of autophagy, its role in host defense and immunity, and selective autophagy, while serving as an excellent reference for more experienced scientists and clinicians looking to update their knowledge. \u003c\/p\u003e \u003cp\u003e\u003cb\u003eVolumes in the Series\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eVolume 1: Molecular Mechanisms.\u003c\/b\u003e Elucidates autophagy's association with numerous biological processes, including cellular development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. \u003cb\u003eVolume 2: Role in General Diseases.\u003c\/b\u003e Describes the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general diseases. \u003cb\u003eVolume 3: Role in Specific Diseases.\u003c\/b\u003e Explores the role of autophagy in specific diseases and developments, including: Crohn's Disease, Gaucher Disease, Huntington's Disease, HCV infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor development and cancer, as well as the relationship between autophagy and apoptosis.\u003cb\u003eVolume 4: Mitophagy.\u003c\/b\u003e Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson Disease, cardiac aging, and skeletal muscle atrophy. \u003cb\u003eVolume 5: Role in Human Diseases.\u003c\/b\u003e Comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer; and the duality of autophagy's effects in various cardiovascular, metabolic, and neurodegenerative disorders.\u003cb\u003eVolume 6: Regulation of Autophagy and Selective Autophagy.\u003c\/b\u003e Provides coverage of the mechanisms of regulation of autophagy; intracellular pathogen use of the autophagy mechanism; the role of autophagy in host immunity; and selective autophagy. \u003cb\u003eVolume 7: Role of Autophagy in Therapeutic Applications.\u003c\/b\u003e Provides coverage of the latest developments in autophagosome biogenesis and regulation; the role of autophagy in protein quality control; the role of autophagy in apoptosis; autophagy in the cardiovascular system; and the relationships between autophagy and lifestyle. \u003cb\u003eVolume 8: Autophagy and Human Diseases.\u003c\/b\u003e Reviews recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, and introduces new, more effective therapeutic strategies, in the development of targeted drugs and programmed cell death, providing information that will aid on preventing detrimental inflammation.\u003cb\u003eVolume 9: Necrosis and Inflammation in Human Diseases.\u003c\/b\u003e Emphasizes the role of Autophagy in necrosis and inflammation, explaining in detail the molecular mechanism(s) underlying the formation of autophagosomes, including the progression of Omegasomes to autophagosomes.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e M. A. Hayat\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0128010320\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780128010327\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Academic Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 01\/05\/2015\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 338\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover","brand":"M. A. Hayat","offers":[{"title":"Hardcover","offer_id":48112838770943,"sku":"9780128010327","price":200.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_c0036686-311f-415f-9f3e-a78896ef3b8b.jpg?v=1769611283","url":"https:\/\/www.whiterainbookhouse.com\/products\/autophagy-m-a-hayat-9780128010327","provider":"WR Book House","version":"1.0","type":"link"}