{"product_id":"axons-and-brain-architecture-kathleen-rockland-9780128013939","title":"Axons and Brain Architecture","description":"\u003cp\u003eSeveral excellent monographs exist which deal with axons. These, however, focus either on the cellular and molecular biology of axons proper or on network organization of connections, the latter with only an incidental or abstract reference to axons \u003ci\u003eper se\u003c\/i\u003e. Still relatively neglected, however, is the middle ground of terminations and trajectories of single axons in the mammalian central nervous system. This middle level of connectivity, between networks on the one hand and local, \u003ci\u003ein vitro\u003c\/i\u003e investigations on the other, is to some extent represented by retrograde tracer studies and labeled neurons, but there have so far been many fewer of the complementary anterograde studies, with total visualization of the axonal arborization.\u003c\/p\u003e \u003cp\u003eThe present volume brings together in one source an interrelated treatment of single axons from the perspective of microcircuitry and as substrates of larger scale organization (tractography). Especially for the former area - axons in microcircuitry - an abundance of published data exists, but these are typically in specialty journals that are not often accessed by the broader community. By highlighting and unifying the span from microcircuitry to tractography, the proposed volume serves as a convenient reference source and in addition inspires further interactions between what currently tend to be separate communities. The volume also redresses the imbalance between \u003ci\u003ein vitro\u003c\/i\u003e\/local connectivity and long-distance connections.\u003c\/p\u003e \u003cp\u003eFocusing on mammalian systems, Part 1 of this book is devoted to anatomical investigations of connections at the single axon level, drawing on modern techniques and classical methods from the 1990s. A particular emphasis is on broad coverage of cortical and subcortical connections from different species, so that common patterns of divergence, convergence, and collateralization can be easily appreciated. Part 2 addresses mechanisms of axon guidance, as these seem particularly relevant to pathways and branching patterns. Part 3 covers axon dynamics and functional aspects; and Part 4 focuses on tractography, notably including comparisons between histological substrates and imaging. \u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Kathleen Rockland\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0128013931\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780128013939\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Academic Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 12\/12\/2015\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 426\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 3.15lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 11.00h x 8.50w x 1.00d","brand":"Kathleen Rockland","offers":[{"title":"Hardcover","offer_id":48112839229695,"sku":"9780128013939","price":125.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_f1ee34a4-2abf-4c6d-a283-9259e15d41ef.jpg?v=1769611287","url":"https:\/\/www.whiterainbookhouse.com\/products\/axons-and-brain-architecture-kathleen-rockland-9780128013939","provider":"WR Book House","version":"1.0","type":"link"}