{"product_id":"bacterial-toxins-thomas-proft-9781908230287","title":"Bacterial Toxins: Genetics, Cellular Biology and Practical Applications","description":"\u003cp\u003eToxins are virulence determinants that play an important role in microbial pathogenicity and\/or evasion of the host immune response. This makes them ideal targets for the development of novel antimicrobial strategies. The potential applications of toxin research extend beyond simply combating microbial pathogens and include use as novel anti-cancer drugs and other front-line medicines and as tools in neurobiology. In the field of cellular biology, toxins have become invaluable as tools for the manipulation and investigation of fundamental cellular and physiological processes. Research in this area is thriving and at a very exciting stage. This timely volume serves as an update on the most important recent advances in the genetics, cellular biology and practical applications of the most important bacterial toxins. Written by internationally respected scientists from eight different countries, topics reviewed include: the molecular basis and risk factors for verotoxin pathogenesis; molecular mechanisms of \u003cem\u003eHelicobacter pylori \u003c\/em\u003eCagA translocation and function; structure and mechanisms of action of pore-forming toxins; bacterial enterotoxins as immunomodulators and vaccine adjuvants; mobile genetic elements as carriers for bacterial virulence genes; the novel family of staphylococcal superantigen-like toxins (SSLs); new insights into the use of botulinum neurotoxins as therapeutics; microbial toxins as tools in cell biology; the role of the large clostridial cytotoxins in \u003cem\u003eC. difficile \u003c\/em\u003edisease. Essential reading for everyone with an interest in bacterial toxins and recommended book for researchers interested in microbial genomics and microbial pathogenesis.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Thomas Proft\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1908230282\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781908230287\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Caister Academic Press Limited\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 08\/01\/2013\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 242\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.60lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.00w x 0.70d","brand":"Thomas Proft","offers":[{"title":"Hardcover","offer_id":48445848584447,"sku":"9781908230287","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_87ec764b-7e8b-4d33-ad02-538e6e1e2e8c.jpg?v=1777221041","url":"https:\/\/www.whiterainbookhouse.com\/products\/bacterial-toxins-thomas-proft-9781908230287","provider":"WR Book House","version":"1.0","type":"link"}