{"product_id":"base-editors-sangsu-bae-9781071628782","title":"Base Editors: Methods and Protocols","description":"\u003cp\u003e\u003cb\u003ePart I: Overview of BEs, Diverse Variants of BEs, and Computational Tools for Bes\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1. Introduction and Perspectives of DNA Base Editors\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e Beomjong Song and Sangsu Bae\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003e2. Web-Based Computational Tools for Base Editors\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e Gue-Ho Hwang and Sangsu Bae\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cb\u003e3. Prediction of Base Editing Efficiencies and Outcomes Using DeepABE and DeepCBE\u003c\/b\u003e\u003cp\u003e\u003c\/p\u003e \u003cp\u003e Jinman Park and Hui Kwon Kim\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003e4. Profiling Genome-Wide Specificity of dCpf1 Cytidine Base Editors Using Digenome-Seq\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e Daesik Kim\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II: Application of BEs for Disease Modeling\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5. Base Editing of Human Hematopoietic Stem Cells\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e Jing Zeng, Gabriele Casirati, My Anh Nguyen, Pietro Genovese, and Daniel E. Bauer\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003e6. A\/C Simultaneous Conversion Using the Dual Base Editor in Human Cells\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e Xiaohui Zhang, Yuting Guan, and Dali Li\u003c\/p\u003e \u003cp\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7. Functional Analysis of Variants in BRCA1 Using CRISPR Base-Editors\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e Ji-Eun See and Yongsub Kim\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003e8. Use of the Representative Base Editing Tool Target-AID to Introduce Pathogenic Mutations into Mice\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e Hiroki Sasaguri\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003e9. Targeted Mutagenesis in Mice Using a Base Editor\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e Tae Yeong Jeong, Soo-Yeon Lim, Je Kyung Seong, and Kyoungmi Kim\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart III: Therapeutic Base Editing Strategies\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10. Heterologous Expression and Purification of a CRISPR-Cas9-Based Adenine Base Editor\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e Seu-Na Lee, Hong-Su Jang, and Jae-Sung Woo\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003e11. Delivering Base Editors In Vivo by Adeno-Associated Virus Vectors\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e Colin K.W. Lim, Angelo J. Miskalis, Pablo Perez-Pinera, and Thomas Gaj\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003e12. The Delivery of ABE mRNA to the Adult Murine Liver by Lipid Nanoparticles (LNPs)\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e Dong Yang and Chun-Qing Song\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003e13. Ex Vivo\u003ci\u003e \u003c\/i\u003eBase Editing Therapy with Chemically-Derived Hepatic Progenitors\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e Yohan Kim, Jaemin Jeong, and Dongho Choi\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003e14. Application of Base Editor-Mediated Genome Editing in Mouse Retina\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e Jun Wu, Chang Sik Cho, Dong Hyun Jo, and Jeong Hun Kim\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart IV: Use of BEs in Plants and Bacteria\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15. High-Throughput Base-Editing-Mediated Artificial Evolution Streamlines Trait Gene Identification in Rice\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e Fang Yan, Man Yu, Meixia Wang, and Huanbin Zhou\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003e16. Heritable Virus-Induced Genome Editing (VIGE) in \u003ci\u003eNicotiana attenuate\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e Hyeonjin Kim, Youngbin Oh, Eunae Park, Moonyoung Kang, Yuri Choi, and Sang-Gyu Kim\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003e17. Cytosine Base Editing in Bacteria\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Sangsu Bae\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 107162878X\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781071628782\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Humana\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 01\/03\/2023\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 235\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.43lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.00w x 0.63d\u003c\/p\u003e","brand":"Sangsu Bae","offers":[{"title":"Hardcover","offer_id":48087527227647,"sku":"9781071628782","price":219.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_ae7e2e53-41d8-41b4-b76d-816e8d75c07b.jpg?v=1769100558","url":"https:\/\/www.whiterainbookhouse.com\/products\/base-editors-sangsu-bae-9781071628782","provider":"WR Book House","version":"1.0","type":"link"}