{"product_id":"bayesian-adaptive-methods-for-clinical-scott-m-berry-9781439825488","title":"Bayesian Adaptive Methods for Clinical Trials","description":"\u003cp\u003eAlready popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug development for a wide variety of diseases and conditions, from Alzheimer's disease and multiple sclerosis to obesity, diabetes, hepatitis C, and HIV. Written by leading pioneers of Bayesian clinical trial designs, \u003cstrong\u003eBayesian Adaptive Methods for Clinical Trials\u003c\/strong\u003e explores the growing role of Bayesian thinking in the rapidly changing world of clinical trial analysis.\u003c\/p\u003e \u003cp\u003e\u003c\/p\u003e \u003cp\u003eThe book first summarizes the current state of clinical trial design and analysis and introduces the main ideas and potential benefits of a Bayesian alternative. It then gives an overview of basic Bayesian methodological and computational tools needed for Bayesian clinical trials. With a focus on Bayesian designs that achieve good power and Type I error, the next chapters present Bayesian tools useful in early (Phase I) and middle (Phase II) clinical trials as well as two recent Bayesian adaptive Phase II studies: the BATTLE and ISPY-2 trials. In the following chapter on late (Phase III) studies, the authors emphasize modern adaptive methods and seamless Phase II-III trials for maximizing information usage and minimizing trial duration. They also describe a case study of a recently approved medical device to treat atrial fibrillation. The concluding chapter covers key special topics, such as the proper use of historical data, equivalence studies, and subgroup analysis.\u003c\/p\u003e \u003cp\u003e\u003c\/p\u003e \u003cp\u003eFor readers involved in clinical trials research, this book significantly updates and expands their statistical toolkits. The authors provide many detailed examples drawing on real data sets. The R and WinBUGS codes used throughout are available on supporting websites.\u003c\/p\u003e Scott Berry talks about the book on the CRC Press YouTube Channel.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Scott M. Berry, Bradley P. Carlin, J. Jack Lee\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1439825483\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781439825488\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e CRC Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 07\/19\/2010\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 324\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.34lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.74h x 6.26w x 0.90d\u003cbr\u003e\u003cbr\u003e\u003cb\u003eReview Citation(s): \u003c\/b\u003e\u003cbr\u003e\u003ci\u003eScitech Book News\u003c\/i\u003e 12\/01\/2010 pg. 71","brand":"Scott M. Berry","offers":[{"title":"Hardcover","offer_id":43980368085247,"sku":"9781439825488","price":140.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_ef745548-3d5e-4a37-a328-492514721033.jpg?v=1683249530","url":"https:\/\/www.whiterainbookhouse.com\/products\/bayesian-adaptive-methods-for-clinical-scott-m-berry-9781439825488","provider":"WR Book House","version":"1.0","type":"link"}