{"product_id":"beta-arrestins-mark-g-h-scott-9781493991570","title":"Beta-Arrestins: Methods and Protocols","description":"\u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis volume looks at various approaches to study the pleiotropic roles of b-arrestins (b-arrs) in the control of signal transduction, and the resulting cellular and in vivo consequences that arise. The chapters in this book cover diverse topics around b-arrs such as their established roles in GPCR regulation and trafficking; regulatory scaffolding functions of b-arrs in MAPK signaling, cAMP hydrolysis and cytoskeletal dynamics; proteomic analysis of the b-arr interactome; mathematical modelling of b-arr signaling networks; functional selectivity involving biased ligands; nucleocytoplasmic trafficking and primary cilia-associated functions of b-arrs; conformational plasticity of b-arrs; and the roles of b-arrs in allergic inflammation, Type 2 Diabetes, Parkinson's disease, and cancer. Written in the highly successful \u003ci\u003eMethods in Molecular Biology \u003c\/i\u003eseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.\u003cbr\u003e\u003c\/p\u003e\u003cbr\u003eCutting-edge and authoritative, \u003ci\u003eBeta-Arrestins: Methods and Protocols \u003c\/i\u003eis a valuable resource for researchers interested in learning more about the function and regulation of b-arrestins.\u003cp\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Mark G. H. Scott\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1493991574\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781493991570\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Humana\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 03\/28\/2019\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 409\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 2.09lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.00w x 0.94d","brand":"Mark G. H. Scott","offers":[{"title":"Hardcover","offer_id":48088404328703,"sku":"9781493991570","price":169.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_88ff6f89-9386-4176-9786-fb1a1130b2e2.jpg?v=1769104644","url":"https:\/\/www.whiterainbookhouse.com\/products\/beta-arrestins-mark-g-h-scott-9781493991570","provider":"WR Book House","version":"1.0","type":"link"}