{"product_id":"biopharmaceuticals-nico-wanandy-9783639136067","title":"Biopharmaceuticals","description":"In the biopharmaceutical industry, essentially, there are three components that play the main role in producing biopharmaceutical products, the host cell, the expression vector and the bioreactor and\/or production environment. To produce the highly valued and desired products, the choice of a suitable host is one of the most important aspects. The host required is not only required to produce the desired product, but also needs to demonstrate robustness in a bioreactor system. Constantly facing challenges in a bioreactor, cells often undergo apoptosis, a well-known limiting factor in biopharmaceutical production, which ultimately leads to low yield of valuable protein(s). We have genetically engineered a CHO-K1 cell line to constitutively express human insulin-like growth factor-1 (IGF-1) and murine polyoma large T-antigen (PyLT-Ag) to generate Super-CHO and CHO-T respectively, two cell lines that can potentially serve different niches in the biopharmaceutical industry.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Nico Wanandy\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 3639136063\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9783639136067\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e VDM Verlag\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 03\/18\/2009\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 264\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 0.86lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.00h x 6.00w x 0.60d","brand":"Nico Wanandy","offers":[{"title":"Paperback","offer_id":48454052544767,"sku":"9783639136067","price":85.32,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_59220ef4-325f-45c2-bb72-93412fc8a34e.jpg?v=1777303898","url":"https:\/\/www.whiterainbookhouse.com\/products\/biopharmaceuticals-nico-wanandy-9783639136067","provider":"WR Book House","version":"1.0","type":"link"}