{"product_id":"breast-cancer-jane-e-visvader-9781621824664","title":"Breast Cancer: From Fundamental Biology to Therapeutic Strategies","description":"Breast cancer is diagnosed in over two million people each year and kills more than six hundred thousand. It has numerous histological subtypes, each with different molecular properties, and a variety of genetic and environmental factors increase an individual's risk of developing the disease. \u003cp\u003e\u003c\/p\u003eWritten and edited by experts in the field, this collection from \u003cem\u003eCold Spring Harbor Perspectives in Medicine\u003c\/em\u003e reviews our understanding of breast cancer epidemiology, the molecular and cellular mechanisms underlying its progression, and recent advances in tumor prevention, detection and treatment. The contributors discuss how work using animal models, patient-derived xenografts, and organoid cultures, together with new imaging approaches, is providing new insights into the molecular pathology of breast cancer. In addition, they examine genetic and genomic determinants, the role of chromatin, and research into intra- and inter-tumor heterogeneity. \u003cp\u003e\u003c\/p\u003eThe authors also discuss tumor dormancy, the importance of the immune system in breast cancer, and ways this may be harnessed in tumor immunotherapy. This volume is therefore a vital reference for all biologists seeking to understand the biological basis of cancer, as well as immunologists and oncologists dedicated to combating this deadly disease.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Jane E. Visvader, Jeffrey M. Rosen, Samuel Aparicio\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1621824667\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781621824664\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Cold Spring Harbor Laboratory Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 01\/31\/2024\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 360\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 2.40lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 5.90h x 7.80w x 1.50d","brand":"Jane E. Visvader","offers":[{"title":"Hardcover","offer_id":46110812078335,"sku":"9781621824664","price":79.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_d2c8d333-e130-480b-bc5e-cb9ad1addba5.jpg?v=1725469852","url":"https:\/\/www.whiterainbookhouse.com\/products\/breast-cancer-jane-e-visvader-9781621824664","provider":"WR Book House","version":"1.0","type":"link"}