{"product_id":"cancer-metastasis-and-cancer-stem-takanori-kawaguchi-9781681083483","title":"Cancer Metastasis and Cancer Stem Cell\/Niche","description":"A malignant tumor is an actively growing tissue, composed of cells derived from a single cell line that has undergone irreversible differentiation. These cells are invasive and also metastasize in the body, resulting in malignant cancer. Recent research suggests that a malignant tumor originates from cancer stem cells (CSC) accompanied with physiological niches. Cancer Metastasis and Cancer Stem Cell\/Niche explains the invasiveness and metastasis of cancer cells in the light of information gained from the CSC \/ niche theory. Five chapters present a review on the fundamental relationships between CSCs, their niche and metastasis, the regulation of cell surface glycan expression in CSCs, tumor endothelial cells and metastasis, toll-like receptor 4 (TLR4)-mediated premetastatic microenvironment, and in surgical cancer metastasis. This monograph is intended as a primary reference on CSC research for physiologists, clinical oncologists, stem cell researchers and molecular biologists.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Takanori Kawaguchi\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1681083485\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781681083483\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Bentham Science Publishers\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 11\/04\/2016\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 158\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 0.86lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.00w x 0.41d","brand":"Takanori Kawaguchi","offers":[{"title":"Paperback","offer_id":43941480628479,"sku":"9781681083483","price":89.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/products\/img_1ec5298b-e0ec-4d3f-871b-61051e8e5578.jpg?v=1681453168","url":"https:\/\/www.whiterainbookhouse.com\/products\/cancer-metastasis-and-cancer-stem-takanori-kawaguchi-9781681083483","provider":"WR Book House","version":"1.0","type":"link"}