{"product_id":"cell-and-matrix-mechanics-roland-kaunas-9781466553811","title":"Cell and Matrix Mechanics","description":"\u003cp\u003eExplores a Range of Multiscale Biomechanics\/Mechanobiology Concepts\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCell and Matrix Mechanics\u003c\/strong\u003e\u003ci\u003e \u003c\/i\u003epresents cutting-edge research at the molecular, cellular, and tissue levels in the field of cell mechanics. This book involves key experts in the field, and covers crucial areas of cell and tissue mechanics, with an emphasis on the roles of mechanical forces in cell-matrix interactions. Providing material in each chapter that builds on the previous chapters, it effectively integrates length scales and contains, for each length scale, key experimental observations and corresponding quantitative theoretical models. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSummarizes the Three Hierarchical Levels of Cell Mechanics\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe book contains 14 chapters and is organized into three sections. The first section focuses on the molecular level, the second section details mechanics at the cellular level, and the third section explores cellular mechanics at the tissue level. The authors offer a thorough description of the roles of mechanical forces in cell and tissue biology, and include specific examples. They incorporate descriptions of associated theoretical models, and provide the data and modeling framework needed for a multi-scale analysis. In addition, they highlight the pioneering studies in cell-matrix mechanics by Albert K. Harris.\u003c\/p\u003e\u003cp\u003eThe topics covered include: \u003c\/p\u003e\u003cul\u003e \u003cp\u003e \u003c\/p\u003e \u003cli\u003eThe passive and active mechanical properties of cytoskeletal polymers and associated motor proteins along with the behavior of polymer networks\u003c\/li\u003e \u003cli\u003eThe mechanical properties of the cell membrane, with an emphasis on membrane protein activation caused by membrane forces\u003c\/li\u003e \u003cli\u003eThe hierarchical organization of collagen fibrils, revealing that a delicate balance exists between specific and nonspecific interactions to result in a structure with semicrystalline order as well as loose associations\u003c\/li\u003e \u003cli\u003eThe roles of matrix mechanical properties on cell adhesion and function along with different mechanical mechanisms of cell-cell interactions\u003c\/li\u003e \u003cli\u003eThe effects of mechanical loading on cell cytoskeletal remodeling, summarizing various modeling approaches that explain possible mechanisms regulating the alignment of actin stress fibers in response to stretching\u003c\/li\u003e \u003cli\u003eThe mechanical testing of cell-populated collagen matrices, along with theory relating the passive and active mechanical properties of the engineered tissues\u003c\/li\u003e \u003cli\u003eCell migration behavior in 3-D matrices and in collective cell motility\u003c\/li\u003e \u003cli\u003eThe role of mechanics in cartilage development\u003c\/li\u003e \u003cli\u003eThe roles of both cellular and external forces on tissue morphogenesis\u003c\/li\u003e \u003cli\u003eThe roles of mechanical forces on tumor growth and cancer metastasis\u003c\/li\u003e \u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eCell and Matrix Mechanics\u003c\/strong\u003e succinctly and systematically explains the roles of mechanical forces in cell-matrix biology. Practitioners and researchers in engineering and physics, as well as graduate students in biomedical engineering and mechanical engineering related to mechanobiology, can benefit from this work. \u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Roland Kaunas\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1466553812\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781466553811\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e CRC Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 10\/23\/2014\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 376\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.98lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.20w x 1.00d","brand":"Roland Kaunas","offers":[{"title":"Hardcover","offer_id":48088309563647,"sku":"9781466553811","price":270.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_99eadf07-78f0-4bd7-be28-60edcdfd932d.jpg?v=1769104197","url":"https:\/\/www.whiterainbookhouse.com\/products\/cell-and-matrix-mechanics-roland-kaunas-9781466553811","provider":"WR Book House","version":"1.0","type":"link"}