{"product_id":"cheminformatics-and-bioinformatics-at-the-aman-chandra-kaushik-9781839161629","title":"Cheminformatics and Bioinformatics at the Interface with Systems Biology: Bridging Chemistry and Medicine","description":"\u003cp\u003eThe cost of drug development is increasing, and investment returns are decreasing. The number of drugs approved by FDA is in decline in terms of the number of new molecular entities (NMEs). Amongst the reasons noted for this are the adverse side effects and reduced efficiency of many of the potential compounds. This is a problem both for the pharmaceutical industry and for those suffering from diseases for which there are no or few available treatments.\u003c\/p\u003e \u003cp\u003eAdvances in computational chemistry, computer science, structural biology and molecular biology have all contributed to improved drug design strategies and reduced the time taken for drug discovery. By interfacing cheminformatics and bioinformatics with systems biology we can create a powerful tool for understanding the mechanisms of patho-physiological systems and identifying lead molecules for various diseases. This integration of drug design approaches can also play a crucial role in the prediction and rationalization of drug effects and side effects, improving safety and efficacy and leading to better approval rates.\u003c\/p\u003e \u003cp\u003eAddressing the lack of knowledge on the fundamental aspects of the various computational tools for drug discovery, this book is a compilation of recent bioinformatics and cheminformatics approaches, and their integration with systems biology. Written primarily for researchers and academics in chem- and bioinformatics, it may also be a useful resource for advanced-level students.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Aman Chandra Kaushik, Aamir Mehmood, Dongqing Wei\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1839161620\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781839161629\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Royal Society of Chemistry\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 09\/08\/2023\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 264\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.25lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.30h x 6.20w x 0.80d","brand":"Aman Chandra Kaushik","offers":[{"title":"Hardcover","offer_id":44073318056191,"sku":"9781839161629","price":220.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_43338b3d-4a7f-41ff-ac79-1ff69e40763e.jpg?v=1685447124","url":"https:\/\/www.whiterainbookhouse.com\/products\/cheminformatics-and-bioinformatics-at-the-aman-chandra-kaushik-9781839161629","provider":"WR Book House","version":"1.0","type":"link"}