{"product_id":"chronic-venous-leg-ulcer-treatment-agency-for-healthcare-resea-and-quality-9781496069221","title":"Chronic Venous Leg Ulcer Treatment: Future Research Needs: Future Research Needs Paper Number 34","description":"Chronic venous leg ulcers affect between 500,000 and 2 million persons annually, and over 50 percent of leg ulcers in the United States are classified as venous ulcers. They are caused by elevated venous pressure, turbulent venous flow, and inadequate venous return that can be due to occlusion or reflux in the venous system. The Johns Hopkins University Evidence-based Practice Center performed a systematic review to determine the effectiveness and safety of advanced wound dressings, systemic antibiotics, and surgical interventions relative to either compression systems or each other among patients with chronic venous leg ulcers. We defined chronic venous leg ulcers as active, noninfected ulcers present for 6 weeks or more with evidence of pre-existing venous disease. An analytic framework was used in the systematic review to describe research gaps. Standard therapy includes aggressive compression with debridement, which heals 50 to 60 percent of venous leg ulcers. Widely used add-on interventions include wound dressings with active components (\"advanced wound dressings\"), local or systemic antimicrobials, and venous surgery. The comparative effectiveness and safety of these advanced wound dressings, antimicrobials and surgical procedures is unclear.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Agency for Healthcare Resea And Quality,U. S. Department of Heal Human Services\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1496069226\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781496069221\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Createspace Independent Publishing Platform\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 02\/25\/2014\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 84\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 0.48lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 11.00h x 8.50w x 0.17d","brand":"Agency for Healthcare Resea And Quality","offers":[{"title":"Paperback","offer_id":48136688861439,"sku":"9781496069221","price":17.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_40095e68-c760-4430-b0bf-a0d80f365c07.jpg?v=1770164191","url":"https:\/\/www.whiterainbookhouse.com\/products\/chronic-venous-leg-ulcer-treatment-agency-for-healthcare-resea-and-quality-9781496069221","provider":"WR Book House","version":"1.0","type":"link"}