{"product_id":"clinical-and-statistical-considerations-in-claudio-carini-9780367378769","title":"Clinical and Statistical Considerations in Personalized Medicine","description":"\u003cp\u003e\u003cem\u003eThe Future of Clinical Research and Health Care: From Empirical to Precision Medicine\u003c\/em\u003e\u003cstrong\u003eClinical and Statistical Considerations in Personalized Medicine\u003c\/strong\u003e explores recent advances related to biomarkers and their translation into clinical development. Leading clinicians, biostatisticians, regulators, commercial professionals, and researchers address the opportunities and challenges in successfully applying biomarkers in drug discovery and preclinical and clinical development.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cem\u003eRobust Biomarkers for Drug Development and Disease Treatment\u003c\/em\u003eThe first four chapters discuss biomarker development from a clinical perspective. Coverage ranges from an introduction to biomarkers to advances in RNAi screens, epigenetics, and rare diseases as targets for personalized medicine approaches. Subsequent chapters examine the statistical considerations in applying a personalized medicine approach, including multiplicity in pharmacogenomics. The last chapter assesses the regulatory issues involved in using biomarkers.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cem\u003eImprove Patient Care and Reduce Costs and Side Effects\u003c\/em\u003eDespite the vast amount of literature on biomarkers, there is no comprehensive book that integrates the clinical and statistical components. This book is one of the first to incorporate both the clinical and statistical aspects of biomarkers in the personalized medicine paradigm. Covering a wide spectrum of personalized medicine-related topics, it presents state-of-the-art techniques for advancing the application of biomarkers in drug discovery and development. \u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Claudio Carini\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0367378760\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780367378769\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e CRC Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 10\/23\/2019\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 376\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.70lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.20h x 6.10w x 0.80d","brand":"Claudio Carini","offers":[{"title":"Paperback","offer_id":48447718031615,"sku":"9780367378769","price":89.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_1a1c7983-4516-4506-bdc6-c9f0e33dd64d.jpg?v=1777234339","url":"https:\/\/www.whiterainbookhouse.com\/products\/clinical-and-statistical-considerations-in-claudio-carini-9780367378769","provider":"WR Book House","version":"1.0","type":"link"}