{"product_id":"clinical-applications-of-capillary-electrophoresis-stephen-m-palfrey-9780896036390","title":"Clinical Applications of Capillary Electrophoresis","description":"The term \"electrophoresis\" was first used by Michaelis in 1909, to - scribe the migration of colloids in an electric field. The first practical elect- phoresis method was described by Tiselius in 1937. He used a U-tube filled with buffer layered on top of sample; migration could be monitored using Schlieren optics. In zone electrophoresis, the U-tube was replaced by paper, a support material employed simply to prevent or minimize diffusion of ions, so that ions applied in a narrow strip to the paper will separate and remain as relatively discrete zones. Paper was superceded by a variety of other media, - cluding cellulose acetate, hydrolyzed starch (starch gel), agarose, and polyacry- mide. The latter, in addition to being a support medium, has size-sieving properties. From the basic zone electrophoresis, other means of separation have been dev- oped. These include, isoelectric focusing, isotachophoresis, density gradient el- trophoresis, and various forms of immunoelectrophoresis. In some ways Capillary Electrophoresis (CE) has gone full circle back to the original method of Tiselius. In its simplest form, separations occur in a buffer solution within a glass (fused silica) tube and detection occurs as sample moves past an optical window. CE has rapidly developed into a technique that rivals HPLC in its versatility. All the classical electrophoretic separations-zone, IEF, and isotachophoresis-have their counterparts in CE. Excitingly so, and - thoritatively treated in Clinical Applications of Capillary Electrophoresis.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Stephen M. Palfrey\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0896036391\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780896036390\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Humana\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 06\/01\/1999\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 212\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.05lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.20h x 6.10w x 0.80d","brand":"Stephen M. Palfrey","offers":[{"title":"Hardcover","offer_id":47422840471807,"sku":"9780896036390","price":109.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_d9d7bf6a-706c-493c-83f5-7490adf0675d.jpg?v=1761528076","url":"https:\/\/www.whiterainbookhouse.com\/products\/clinical-applications-of-capillary-electrophoresis-stephen-m-palfrey-9780896036390","provider":"WR Book House","version":"1.0","type":"link"}