{"product_id":"clinical-biochemistry-made-easy-uthayasooriya-amarasena-9798264826146","title":"Clinical Biochemistry Made Easy: Volume 3: Molecular Biology and Genetics - Blueprint of Life","description":"\u003cb\u003eContent List\u003c\/b\u003e\u003cbr\u003e\u003cb\u003e1. Introduction to Molecular Biology and Genetics\u003c\/b\u003e\u003cbr\u003e1.1 What is Molecular Biology?\u003cbr\u003e1.2 Overview of the Central Dogma\u003cbr\u003e1.3 Nucleic Acids: The Language of Life\u003cbr\u003e1.4 Human Genome Project - Milestones and Relevance\u003cbr\u003e1.5 Organization of the Human Genome (Introns, Exons, Non-coding DNA)\u003cbr\u003e1.6 Clinical Insight: Genetic vs Acquired Disorders\u003cbr\u003e1.7 Story: \"The Code Awakens - Birth of Life's Blueprint\"\u003cbr\u003e1.8 MCQs and SEQs on DNA-RNA basics and genome structure\u003cbr\u003e\u003cb\u003e2. Structure and Function of DNA \u0026amp; RNA\u003c\/b\u003e\u003cbr\u003e2.1 Discovery and History - Watson, Crick, Franklin\u003cbr\u003e2.2 Structure of DNA: Double Helix, Base Pairing, Stability\u003cbr\u003e2.3 Types of RNA: mRNA, tRNA, rRNA, miRNA, snRNA\u003cbr\u003e2.4 Chromatin Structure: Nucleosomes, Histones, Epigenetic Marks\u003cbr\u003e2.5 DNA Supercoiling and Packaging in Eukaryotes\u003cbr\u003e2.6 Clinical Correlation: Histone Modifications in Cancer\u003cbr\u003e2.7 Story: \"The Spiral Script - How DNA Holds the Instructions of Life\"\u003cbr\u003e2.8 Viva Tips: One-liners for RNA types\u003cbr\u003e2.9 Spotters: DNA\/RNA models, histone images\u003cbr\u003e\u003cb\u003e3. DNA Replication, Repair, and Mutation\u003c\/b\u003e\u003cbr\u003e3.1 Semiconservative DNA Replication\u003cbr\u003e3.2 Leading vs Lagging Strand - Okazaki Fragments\u003cbr\u003e3.3 DNA Repair Mechanisms: \u003cbr\u003e3.4 Mutations: Types (Silent, Missense, Nonsense, Frameshift, Triplet Expansion)\u003cbr\u003e3.5 Mutagens and Carcinogenesis\u003cbr\u003e3.6 Clinical Disorders: Xeroderma Pigmentosum, HNPCC, Ataxia-Telangiectasia\u003cbr\u003e3.7 Story: \"The Replicator's Race - Mistakes, Mutants, and the Repair Crew\"\u003cbr\u003e3.8 MCQs, SEQs, VIVA Cards: Mutation examples\u003cbr\u003e3.9 Spot Diagnosis: Mutation types from genetic reports\u003cbr\u003e\u003cb\u003e4. Transcription and Translation\u003c\/b\u003e\u003cbr\u003e\u003cb\u003e4.1 Transcription (DNA to RNA)\u003c\/b\u003e\u003cbr\u003e\u003cb\u003e4.2 Translation (RNA to Protein)\u003c\/b\u003e\u003cbr\u003e4.3 Genetic Code: Characteristics and Clinical Application\u003cbr\u003e4.4 Clinical Correlation: β-Thalassemia, Duchenne Muscular Dystrophy\u003cbr\u003e4.5 Story: \"From Script to Symphony - The Ribosomal Orchestra\"\u003cbr\u003e4.6 Mnemonics: Stop Codons, Codon Tables\u003cbr\u003e4.7 Spotters: Transcription-translation diagrams, histological sections\u003cbr\u003e4.8 OSCE: Interpreting genetic code table for amino acid sequences\u003cbr\u003e\u003cb\u003e5. Gene Expression and Regulation\u003c\/b\u003e\u003cbr\u003e5.1 Operon Model: Lac and Trp Operons (Prokaryotes)\u003cbr\u003e5.2 Gene Expression in Eukaryotes\u003cbr\u003e5.3 Epigenetic Regulation: Methylation, Acetylation\u003cbr\u003e5.4 RNA Interference and miRNA\u003cbr\u003e5.5 Regulation During Development and Differentiation\u003cbr\u003e5.6 Clinical Relevance: Cancer Genetics, Imprinting Disorders (e.g., Prader-Willi, Angelman)\u003cbr\u003e5.7 Story: \"The Gene Gatekeepers - When to Speak, When to Stay Silent\"\u003cbr\u003e5.8 Viva Cards: Gene silencing and gene amplification\u003cbr\u003e5.9 MCQs: Epigenetics and oncogenes\u003cbr\u003e\u003cb\u003e6. Recombinant DNA Technology \u0026amp; PCR\u003c\/b\u003e\u003cbr\u003e6.1 DNA Cloning and Vectors (Plasmid, Bacteriophage, Cosmid)\u003cbr\u003e6.2 Restriction Enzymes and DNA Ligase\u003cbr\u003e6.3 PCR - Principles, Steps, and Applications\u003cbr\u003e6.4 Gel Electrophoresis and Southern, Northern, Western Blot\u003cbr\u003e\u003cb\u003e7. Clinical Genetics and Genetic Counseling\u003c\/b\u003e\u003cbr\u003e\u003cb\u003e8. Molecular Diagnosis of Genetic Disorders\u003c\/b\u003e\u003cbr\u003e\u003cb\u003e9. Clinical Biochemistry Applications in Genetics\u003c\/b\u003e\u003cbr\u003e\u003cb\u003eAppendices \u0026amp; Study Aids\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Uthayasooriya Amarasena\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9798264826146\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Independently Published\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 09\/11\/2025\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 310\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 0.92lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.00h x 6.00w x 0.65d","brand":"Uthayasooriya Amarasena","offers":[{"title":"Paperback","offer_id":47965480386815,"sku":"9798264826146","price":20.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_f19dc950-080b-4899-b9fb-fcc280202d70.jpg?v=1767280851","url":"https:\/\/www.whiterainbookhouse.com\/products\/clinical-biochemistry-made-easy-uthayasooriya-amarasena-9798264826146","provider":"WR Book House","version":"1.0","type":"link"}