{"product_id":"clinical-studies-and-therapies-in-juan-segura-aguilar-9780128221204","title":"Clinical Studies and Therapies in Parkinson's Disease: Translations from Preclinical Models","description":"More than 50 years have passed since the use of L-dopa in the palliative treatment of Parkinson's disease, but it remains the most common treatment despite inducing severe side effects such as dyskinesia after 4-6 years of use. Numerous preclinical investigations based on endogenous neurotoxin models have promised various therapies for Parkinson's disease, but these efforts have failed when attempting to transfer these successful results to preclinical studies. Although several publications have warned of these failures, the scientific community remains mostly unaware, and there is a need to focus their efforts on potential therapeutics that can slow or halt development of the disease. \u003cp\u003e\u003c\/p\u003e\u003ci\u003eClinical Studies and Therapies in Parkinson's Disease: Translations from Preclinical Models\u003c\/i\u003e analyzes preclinical models based on exogenous neurotoxins and why they have failed. Neuroscientists, neurologists, and neuropharmacologists will benefit greatly from the book's discussion of these newer models, their benefits, and the need for their implementation. This book also provides the basic concepts of dopamine metabolism for students taking courses in neurochemistry, neuroscience, neuropharmacology, biochemistry, and medicine.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Juan Segura-Aguilar\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0128221208\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780128221204\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Academic Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 06\/16\/2021\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 306\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback","brand":"Juan Segura-Aguilar","offers":[{"title":"Paperback","offer_id":48112849158399,"sku":"9780128221204","price":150.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_45c6de3d-d05b-42c7-9580-64c12ab941d6.jpg?v=1769611357","url":"https:\/\/www.whiterainbookhouse.com\/products\/clinical-studies-and-therapies-in-juan-segura-aguilar-9780128221204","provider":"WR Book House","version":"1.0","type":"link"}