{"product_id":"clinical-trial-optimization-using-r-alex-dmitrienko-9780367261252","title":"Clinical Trial Optimization Using R","description":"\u003cp\u003e\u003cstrong\u003eClinical Trial Optimization Using R\u003c\/strong\u003e explores a unified and broadly applicable framework for optimizing decision making and strategy selection in clinical development, through a series of examples and case studies. It provides the clinical researcher with a powerful evaluation paradigm, as well as supportive R tools, to evaluate and select among simultaneous competing designs or analysis options. It is applicable broadly to statisticians and other quantitative clinical trialists, who have an interest in optimizing clinical trials, clinical trial programs, or associated analytics and decision making.\u003c\/p\u003e\u003cp\u003eThis book presents in depth the Clinical Scenario Evaluation (CSE) framework, and discusses optimization strategies, including the quantitative assessment of tradeoffs. A variety of common development challenges are evaluated as case studies, and used to show how this framework both simplifies and optimizes strategy selection. Specific settings include optimizing adaptive designs, multiplicity and subgroup analysis strategies, and overall development decision-making criteria around Go\/No-Go. After this book, the reader will be equipped to extend the CSE framework to their particular development challenges as well.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Alex Dmitrienko\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0367261251\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780367261252\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e CRC Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 03\/22\/2019\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 319\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.05lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.21h x 6.14w x 0.71d","brand":"Alex Dmitrienko","offers":[{"title":"Paperback","offer_id":44809611739391,"sku":"9780367261252","price":59.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_525b4296-3cc2-4886-a38d-e44528d65522.jpg?v=1707926983","url":"https:\/\/www.whiterainbookhouse.com\/products\/clinical-trial-optimization-using-r-alex-dmitrienko-9780367261252","provider":"WR Book House","version":"1.0","type":"link"}