{"product_id":"clostridia-holger-brzggemann-9781904455387","title":"Clostridia: Molecular Biology in the Post-genomic Era","description":"\u003cp\u003eThe genus \u003cem\u003eClostridium \u003c\/em\u003erepresents a heterogeneous group of anaerobic spore-forming bacteria, comprising prominent toxin-producing species, such as \u003cem\u003eC. difficile\u003c\/em\u003e, \u003cem\u003eC. botulinum\u003c\/em\u003e, \u003cem\u003eC. tetani\u003c\/em\u003e and \u003cem\u003eC. perfringens\u003c\/em\u003e, in addition to well-known non-pathogens like solventogenic \u003cem\u003eC. acetobutylicum\u003c\/em\u003e. In the last decade several clostridial genomes have been deciphered and post-genomic studies are currently underway. The advent of newly developed, genetic manipulation tools have permitted functional-based and systems biology analyses of several clostridial strains. Research in this area is at a very exciting stage. In this book internationally recognised \u003cem\u003eClostridium \u003c\/em\u003eexperts critically review the most important aspects of clostridial research, providing the first coherent picture of the organism's molecular and cellular biology in this post-genomic era. The first major focus of the book is the genetics and molecular biology of the major clostridial toxins including: botulinum and tetanus neurotoxins, \u003cem\u003eC. difficile\u003c\/em\u003elarge exotoxins, \u003cem\u003eC. perfringens\u003c\/em\u003e enterotoxin, pore-forming and binary bacterial toxins. Other topics include: molecular epidemiology of \u003cem\u003eC. botulinum\u003c\/em\u003e and \u003cem\u003eC. difficile\u003c\/em\u003e, metabolic networks in \u003cem\u003eC. acetobutylicum\u003c\/em\u003e, development of genetic knock-out systems for clostridia, surface structures, anti tumor potential of clostridia, and antibiotic resistance determinants in \u003cem\u003eC. difficile\u003c\/em\u003e. Essential reading for every clostridia researcher, from the PhD student to the experienced scientist, as it provides a timely review of current research.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Holger Brüggemann\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1904455387\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781904455387\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Caister Academic Press Limited\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 01\/01\/2009\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 242\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.50lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.90h x 7.10w x 0.70d\u003cbr\u003e\u003cbr\u003e\u003cb\u003eReview Citation(s): \u003c\/b\u003e\u003cbr\u003e\u003ci\u003eScitech Book News\u003c\/i\u003e 03\/01\/2009 pg. 73","brand":"Holger Brüggemann","offers":[{"title":"Hardcover","offer_id":48217571623167,"sku":"9781904455387","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_9803062d-948b-4d1c-9bae-afac57d854ea.jpg?v=1771998078","url":"https:\/\/www.whiterainbookhouse.com\/products\/clostridia-holger-brzggemann-9781904455387","provider":"WR Book House","version":"1.0","type":"link"}