{"product_id":"computational-epigenetics-and-crispr-jamie-flux-9798300348991","title":"Computational Epigenetics and CRISPR - Programming Tools for DNA Methylation Editing: With R and Bioconductor","description":"\u003cp\u003eEmbark on a transformative journey through the cutting-edge realms of computational epigenetics and CRISPR-based DNA methylation editing. This comprehensive volume serves as an indispensable resource for researchers, bioinformaticians, and advanced practitioners seeking to explore the intricate mechanisms of epigenetic regulation and leverage state-of-the-art computational tools.\u003c\/p\u003e \u003cp\u003eSpanning 64 in-depth chapters, the book delves into advanced concepts and innovative methodologies that push the boundaries of current scientific understanding. Readers will gain profound insights into high-resolution epigenomic mapping techniques, sophisticated Bioconductor workflows, and the integration of multi-omics data to unravel the dynamic nature of the epigenome.\u003c\/p\u003e \u003cp\u003eKey features include: \u003c\/p\u003e \u003cul\u003e\u003cli\u003e\n\u003cb\u003eAdvanced Computational Frameworks\u003c\/b\u003e: Explore machine learning approaches, including deep learning models and artificial intelligence, tailored for epigenetic data integration and pattern recognition.\u003c\/li\u003e\u003c\/ul\u003e \u003cul\u003e\u003cli\u003e\n\u003cb\u003eSingle-Cell and Spatial Epigenomics\u003c\/b\u003e: Dive into the complexities of single-cell epigenomic data analysis and spatially-resolved methylation mapping, addressing computational challenges and pioneering solutions.\u003c\/li\u003e\u003c\/ul\u003e \u003cul\u003e\u003cli\u003e\n\u003cb\u003eCRISPR-Based Epigenome Editing\u003c\/b\u003e: Gain expertise in designing highly specific guide RNAs, simulating epigenetic interventions, and predicting genome-wide effects using CRISPR\/dCas9 fusion proteins.\u003c\/li\u003e\u003c\/ul\u003e \u003cul\u003e\u003cli\u003e\n\u003cb\u003eSynthetic Epigenomics and Epigenetic Therapies\u003c\/b\u003e: Learn about engineering custom DNA methylation landscapes, computational design of epigenetic therapies, and virtual screening techniques for small molecules.\u003c\/li\u003e\u003c\/ul\u003e \u003cul\u003e\u003cli\u003e\n\u003cb\u003eInterdisciplinary Perspectives\u003c\/b\u003e: Benefit from integrative approaches that encompass neurobiology, immunology, plant biology, endocrinology, and more, highlighting the broad applicability of epigenetic research.\u003c\/li\u003e\u003c\/ul\u003e \u003cul\u003e\u003cli\u003e\n\u003cb\u003eInnovative Methodologies\u003c\/b\u003e: Stay ahead with chapters on stochastic modeling, network analysis, mathematical modeling of epigenetic landscapes, and the development of bioinformatics pipelines for high-throughput data.\u003c\/li\u003e\u003c\/ul\u003e \u003cul\u003e\u003cli\u003e\n\u003cb\u003ePractical Applications with R and Bioconductor\u003c\/b\u003e: Implement advanced analytical techniques using practical examples and tutorials that leverage the robust capabilities of R and Bioconductor packages.\u003c\/li\u003e\u003c\/ul\u003e \u003cp\u003eThis authoritative text not only presents the latest research breakthroughs but also introduces original theoretical frameworks and proposes novel methodologies. It challenges conventional perspectives by exploring uncharted territories and integrating interdisciplinary insights, fostering a deeper understanding of epigenetic regulation and its implications for health and disease.\u003c\/p\u003e \u003cp\u003eWhether you are seeking to enhance your research, develop innovative solutions, or contribute to the forefront of epigenetic science, this book provides the knowledge and tools necessary to pioneer new horizons in the field. Embrace the opportunity to expand your expertise and shape the future of computational epigenetics and DNA methylation editing.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Jamie Flux\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9798300348991\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Independently Published\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 11\/18\/2024\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 416\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.22lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.00h x 6.00w x 0.85d","brand":"Jamie Flux","offers":[{"title":"Paperback","offer_id":48454145507583,"sku":"9798300348991","price":69.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_11cf4d31-e37b-425f-b872-14644cdc20c9.jpg?v=1777304442","url":"https:\/\/www.whiterainbookhouse.com\/products\/computational-epigenetics-and-crispr-jamie-flux-9798300348991","provider":"WR Book House","version":"1.0","type":"link"}