{"product_id":"computational-methods-in-protein-evolution-tobias-sikosek-9781493987351","title":"Computational Methods in Protein Evolution","description":"\u003cp\u003eThis volume presents a diverse collection of methodologies used to study various problems at the protein sequence and structure level. The chapters in this book look at issues ranging from broad concepts like protein space to specifics like antibody modeling. Topics include point mutations, gene duplication, \u003ci\u003ede novo\u003c\/i\u003e emergence of new genes, pairwise correlated mutations, ancestral protein reconstruction, homology modelling, protein stability and dynamics, and protein-protein interactions. The book also covers a wide range of computational approaches, including sequence and structure alignments, phylogenies, physics-based and mathematical approaches, machine learning, and more. Written in the highly successful \u003ci\u003eMethods in Molecular Biology\u003c\/i\u003e series format, chapters include introductions to their respective topics, lists of the necessary materials and prerequisites, step-by-step, readily reproducible computational protocols (using command line or graphical user interfaces, sometimes including computer code), and tips on troubleshooting and avoiding known pitfalls. \u003c\/p\u003e\u003cp\u003e\u003c\/p\u003eCutting-edge and authoritative, \u003ci\u003eComputational Methods in Protein Evolution\u003c\/i\u003e is a valuable resource that offers useful workflows and techniques that will help both novice and expert researchers working with proteins computationally.\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Tobias Sikosek\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1493987356\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781493987351\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Humana\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 10\/09\/2018\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 420\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 2.30lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.20h x 7.40w x 1.00d","brand":"Tobias Sikosek","offers":[{"title":"Hardcover","offer_id":48088401707263,"sku":"9781493987351","price":199.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_4752702a-82cc-49a2-9d9c-c9fb60ce12d9.jpg?v=1769104630","url":"https:\/\/www.whiterainbookhouse.com\/products\/computational-methods-in-protein-evolution-tobias-sikosek-9781493987351","provider":"WR Book House","version":"1.0","type":"link"}