{"product_id":"computational-systems-biology-with-constraints-luca-bortolussi-9783639088755","title":"Computational Systems Biology with Constraints","description":"Recently, stochastic process algebras have been used for modeling biological systems, as they provide a simple, compositional language to define biological models. Classical process algebras, however, require to express everything in terms of communications, a limiting restriction when structured information needs to be processed. In this book, we tackle this problem using a more general language and programming it to deal with the domain of interest. Specifically, we introduce a sto-chastic extension (sCCP) of Concurrent Constraint Programming. It is precisely the use of constraints that gives flexibility and extendibility to the language, together with the presence of context-dependent stochastic rates. To prove this, we show how sCCP can be used to model a wide range of biological systems, from biochemical networks to the process of folding of a protein, providing evidence that the use of constraints simplifies the process of modeling and allows to incorporate external knowledge. Many analysis tools are developed: stochastic simulation, model checking, ODE-based approximations. The book can be of interest to researchers working in the field of computational systems biology.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Luca Bortolussi\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 3639088751\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9783639088755\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e VDM Verlag Dr. Mueller E.K.\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 10\/17\/2008\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 248\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 0.74lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.00h x 6.00w x 0.52d","brand":"Luca Bortolussi","offers":[{"title":"Paperback","offer_id":48217631129855,"sku":"9783639088755","price":85.32,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_c6b325e6-4bde-456c-9b51-82405ef39030.jpg?v=1771998437","url":"https:\/\/www.whiterainbookhouse.com\/products\/computational-systems-biology-with-constraints-luca-bortolussi-9783639088755","provider":"WR Book House","version":"1.0","type":"link"}