{"product_id":"cytochrome-p450-2d6-shufeng-zhou-9780367658595","title":"Cytochrome P450 2D6: Structure, Function, Regulation and Polymorphism","description":"\u003cp\u003eCytochromes are proteins\u003cb\u003e \u003c\/b\u003ethat catalyze electron transfer reactions of well-known metabolic pathways and are classified in various superfamilies. The CYP, or P450, superfamily accounts for 90% of the oxidative metabolism of clinical drugs. One member of this superfamily, P450 2D6 (or CYP2D6), singlehandedly metabolizes about 25% of all medications in the human liver. \u003cb\u003eCytochrome P450 2D6: Structure, Function, Regulation, and Polymorphism\u003c\/b\u003e reviews the current knowledge of CYP2D6 as well as the maturing body of evidence indicating its significance to clinical and pharmacological researchers and practitioners.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003eThis book focuses on the critical role CYP2D6 plays in the human liver. It examines the genetic, epigenetic, physiological, pathological, and structural factors of the gene that govern the highly variable metabolism of a number of drugs in clinical use. It highlights the impact of the functional roles of CYP2D6 on clinical practice and drug development and also discusses implications for precise medicine, strategies to avoid adverse drug reactions, and paths for future research.\u003c\/p\u003e\u003cb\u003e\u003cbr\u003e\u003cbr\u003e\u003c\/b\u003e\u003cp\u003eCytochrome P450 2D6 is a unique, valuable book focusing on a single but immensely powerful human gene. It provides the first single source of comprehensive information on CYP2D6 that serves as an important reference for medical, biomedical, pharmaceutical, and nursing researchers, practitioners, and students.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Shufeng Zhou\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0367658593\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780367658595\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e CRC Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 09\/30\/2020\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 508\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 2.58lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 11.00h x 8.25w x 1.06d","brand":"Shufeng Zhou","offers":[{"title":"Paperback","offer_id":45064691187967,"sku":"9780367658595","price":59.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_3e3e9d01-f5bd-482d-8ad0-b1d1ae9379ec.jpg?v=1712124825","url":"https:\/\/www.whiterainbookhouse.com\/products\/cytochrome-p450-2d6-shufeng-zhou-9780367658595","provider":"WR Book House","version":"1.0","type":"link"}