{"product_id":"death-receptors-in-cancer-therapy-wafik-s-el-deiry-9781617374012","title":"Death Receptors in Cancer Therapy","description":"An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Topics of particular interest include resistance to apoptosis, TRAIL signaling, death receptors in embryonic development, mechanisms of caspase activation, and death receptor mutations in cancer. Additional chapters address death signaling in melanoma, synthetic retinoids and death receptors, the role of p53 in death receptor regulation, immune suppression of cancer, and combination therapy with death ligands.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Wafik S. El-Deiry\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1617374016\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781617374012\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Humana\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 11\/19\/2010\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 374\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.48lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.00w x 0.80d","brand":"Wafik S. El-Deiry","offers":[{"title":"Paperback","offer_id":47424446234879,"sku":"9781617374012","price":119.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_2421caa5-8639-4771-9bd2-499b828e099e.jpg?v=1761530274","url":"https:\/\/www.whiterainbookhouse.com\/products\/death-receptors-in-cancer-therapy-wafik-s-el-deiry-9781617374012","provider":"WR Book House","version":"1.0","type":"link"}