{"product_id":"dna-encoded-chemical-libraries-david-israel-9781071625446","title":"Dna-Encoded Chemical Libraries: Methods and Protocols","description":"\u003cp\u003eThis volume discusses protocols that cover synthesis, screening by selection, and analysis of DNA-encoded chemical libraries (DEL). Chapters in this book focus on methods used to practice DEL technology and include solution phase library synthesis using a variety of chemistries; DNA encoding of chemical structure; design, preparation and analysis of target proteins and tool compounds; screening of soluble protein targets by affinity selection; DEL qPCR, preparative PCR and DNA sequence analysis; computational methods used to analyze selections and choose compounds for resynthesis; and analysis of hit compounds. Written in the highly successful \u003ci\u003eMethods in Molecular Biology\u003c\/i\u003e series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. \u003c\/p\u003e\u003cp\u003e\u003c\/p\u003eCutting-edge and comprehensive, \u003ci\u003eDNA-Encoded Chemical Libraries: Methods and Protocols\u003c\/i\u003e is a valuable resource for scientists interested in DEL technology for drug discovery, and will contribute to the continued advancement in this important field.\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e David Israel\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1071625446\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781071625446\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Humana\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 09\/10\/2022\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 226\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.39lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.00w x 0.56d","brand":"David Israel","offers":[{"title":"Hardcover","offer_id":44072648474879,"sku":"9781071625446","price":169.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_e87df2fe-2e73-4dfa-9502-11cc3be19a90.jpg?v=1685443204","url":"https:\/\/www.whiterainbookhouse.com\/products\/dna-encoded-chemical-libraries-david-israel-9781071625446","provider":"WR Book House","version":"1.0","type":"link"}