{"product_id":"dna-repair-in-cancer-therapy-mark-r-kelley-9780128035825","title":"DNA Repair in Cancer Therapy: Molecular Targets and Clinical Applications","description":"\u003cp\u003e\u003ci\u003eDNA Repair and Cancer Therapy: Molecular Targets and Clinical Applications, Second Edition\u003c\/i\u003e provides a comprehensive and timely reference that focuses on the translational and clinical use of DNA repair as a target area for the development of diagnostic biomarkers and the enhancement of cancer treatment. \u003c\/p\u003e \u003cp\u003eExperts on DNA repair proteins from all areas of cancer biology research take readers from bench research to new therapeutic approaches. This book provides a detailed discussion of combination therapies, in other words, how the inhibition of repair pathways can be coupled with chemotherapy, radiation, or DNA damaging drugs. \u003c\/p\u003e \u003cp\u003eNewer areas in this edition include the role of DNA repair in chemotherapy induced peripheral neuropathy, radiation DNA damage, Fanconi anemia cross-link repair, translesion DNA polymerases, BRCA1-BRCA2 pathway for HR and synthetic lethality, and mechanisms of resistance to clinical PARP inhibitors. \u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Mark R. Kelley\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 012803582X\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780128035825\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Academic Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 06\/21\/2016\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 464\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 2.47lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.40h x 7.60w x 1.10d","brand":"Mark R. Kelley","offers":[{"title":"Hardcover","offer_id":48135922942207,"sku":"9780128035825","price":160.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_60f11a09-add4-4ed0-a338-0959194c7b0e.jpg?v=1770159342","url":"https:\/\/www.whiterainbookhouse.com\/products\/dna-repair-in-cancer-therapy-mark-r-kelley-9780128035825","provider":"WR Book House","version":"1.0","type":"link"}