{"product_id":"drug-metabolism-and-pharmacokinetics-liang-shen-9781394300129","title":"Drug Metabolism and Pharmacokinetics: Frontiers, Strategies, and Applications","description":"\u003cp\u003e\u003cb\u003ePractical, state-of-the-art pharmacokinetic research methods, ideas, advancements, applications, and strategies\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eDrawing on a wealth of extensive practical experience and theoretical research, \u003ci\u003eDrug Metabolism and Pharmacokinetics\u003c\/i\u003e encapsulates the most recent advancements and illustrative applications in the field. Sixty-eight relatively independent yet interconnected articles are included, each offering a unique perspective and providing in-depth interpretation. Readers can either read systematically or select specific topics of interest from the table of contents. \u003c\/p\u003e\u003cp\u003eBasic concepts, frontier advancements, DMPK research strategies, and technical methods are covered for novel drug modalities and therapeutics in different disease areas. The book encompasses a wide range of application and validation cases for DMPK research, including studies in \u003ci\u003ein vitro\u003c\/i\u003e ADME, \u003ci\u003ein vivo\u003c\/i\u003e pharmacokinetics, metabolite profiling and identification, radiolabeled ADME, and bioanalysis. Case studies showing the application of topics covered are included throughout, along with valuable insights into problem-solving and critical thinking. \u003c\/p\u003e\u003cp\u003eWritten by a team of scientists specializing in DMPK research from the DMPK Department of WuXi AppTec, \u003ci\u003eDrug Metabolism and Pharmacokinetics\u003c\/i\u003e discusses sample topics including: \u003c\/p\u003e\u003cul\u003e \u003cli\u003eADME characteristics, metabolite identification, and bioanalytical strategies for oligonucleotide drugs\u003c\/li\u003e \u003cli\u003eStrategy and challenges in the determination of drug-to-antibody ratio (DAR) values and antibody-drug conjugates (ADCs)\u003c\/li\u003e \u003cli\u003eBreaking barriers in CNS drug development with intrathecal and intracerebroventricular administration\u003c\/li\u003e \u003cli\u003eApplication and detection techniques of biomarkers in drug development\u003c\/li\u003e \u003cli\u003eFlux dialysis methods for assessing plasma protein binding of high protein-binding drugs\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eDrug Metabolism and Pharmacokinetics is an essential forward-thinking reference on the subject for pharmacy students, pharmaceutical industry researchers, and DMPK scientists, especially those exploring novel drug modalities.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Liang Shen\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1394300123\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781394300129\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Wiley\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 07\/09\/2025\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 576\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003c\/p\u003e","brand":"Liang Shen","offers":[{"title":"Hardcover","offer_id":47202874294527,"sku":"9781394300129","price":285.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_281eeac6-ad63-456e-b99e-655988d19992.jpg?v=1756833664","url":"https:\/\/www.whiterainbookhouse.com\/products\/drug-metabolism-and-pharmacokinetics-liang-shen-9781394300129","provider":"WR Book House","version":"1.0","type":"link"}