{"product_id":"endocrine-manifestations-of-systemic-autoimmune-ronald-asherson-9780444531728","title":"Endocrine Manifestations of Systemic Autoimmune Diseases: Volume 9","description":"This book is one of the first to evaluate the role of Steroids in autoimmune rheumatic diseases from the basic mechanisms to the clinical involvements and focuses on the importance of steroidal hormones in the pathogenesis and therapeutic management of the autoimmune rheumatic diseases. In particular, the chapters analyze the mechanisms of action and the involvement of adrenal steroids (glucocorticoids) in the neuroendocrine immune system, including effects on the elderly. The perturbations of the HPA axis as a source of altered steroidal synthesis will be discussed and related to some interesting pathological conditions that commonly complicate the autoimmune rheumatic diseases such as psychosis or fibromyalgia. Concerning the role of gonadal steroids (sex hormones), several chapters will discuss clinical and epidemiological evidences of their role, as well as their effects as risk factors in autoimmune rheumatic diseases, including a section on pediatrics.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Ronald Asherson\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0444531726\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780444531728\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Elsevier Science\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 05\/01\/2008\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 340\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 2.25lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.49h x 7.55w x 0.81d","brand":"Ronald Asherson","offers":[{"title":"Hardcover","offer_id":48112909385983,"sku":"9780444531728","price":230.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_4ac1dced-1718-4729-9c54-710226550cc6.jpg?v=1769611764","url":"https:\/\/www.whiterainbookhouse.com\/products\/endocrine-manifestations-of-systemic-autoimmune-ronald-asherson-9780444531728","provider":"WR Book House","version":"1.0","type":"link"}