{"product_id":"epilepsy-jong-rho-9781420085594","title":"Epilepsy: Mechanisms, Models, and Translational Perspectives","description":"\u003cp\u003eEpilepsy has afflicted humankind throughout recorded history; yet, it is only in the last half-century, that significant progress has been made in our basic understanding of the epileptic brain. Pivotal advances in drug development and surgical techniques, as well as the emergence of innovative approaches such as electrical stimulation of the nervous system, have led to a substantial reduction in the morbidity and mortality of patients with epilepsy. At the same time, remarkable developments in neuroscience have enhanced our understanding of brain structure and function.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eEpilepsy: Mechanisms, Models, and Translational Perspectives \u003c\/strong\u003eincorporates new translational advances that bring epilepsy therapies from the laboratory bench to the bedside and back again. It brings together the work of more than 70 of the field's most respected and cutting-edge researchers and clinicians. In 24 chapters, this extraordinarily comprehensive and current work: \u003c\/p\u003e\u003cp\u003e\u003c\/p\u003eOffers an overview of the basic anatomic and functional substrates of seizure genesis and considers novel pathogenic concepts that have both emerged and been validated experimentally\u003cp\u003e\u003c\/p\u003e\u003cul\u003e \u003cp\u003e\u003c\/p\u003e\n\u003cli\u003eExamines antiepileptic drug therapy, including the latest on molecular targets \u003c\/li\u003e \u003cp\u003e\u003c\/p\u003e\n\u003cli\u003eLooks at the state of surgical treatments for epilepsy and discusses advances in the fields of structural and functional neuroimaging \u003c\/li\u003e \u003cp\u003e\u003c\/p\u003e\n\u003cli\u003eReviews the variety of nontraditional therapeutic options, such as the ketogenic diet, the vagus nerve stimulator, immunomodulators, neurosteroids, herbs, and botanicals \u003c\/li\u003e \u003cp\u003e\u003c\/p\u003e\n\u003cli\u003eInvestigates neuroendocrine, hormonal, and biobehavioral factors that influence seizure susceptibility--information that can be incorporated into the design of treatment algorithms on an individualized basis \u003c\/li\u003e \u003cp\u003e\u003c\/p\u003e\n\u003cli\u003eProvides a glimpse of what future epilepsy therapies might look like, from novel mechanisms of drug delivery to gene and stem-cell therapies for epilepsy to seizure detection meth\u003c\/li\u003e \u003c\/ul\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Jong Rho\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 142008559X\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781420085594\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e CRC Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 04\/01\/2009\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 684\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cbr\u003e\u003cb\u003eReview Citation(s): \u003c\/b\u003e\u003cbr\u003e\u003ci\u003eScitech Book News\u003c\/i\u003e 12\/01\/2010 pg. 88","brand":"Jong Rho","offers":[{"title":"Hardcover","offer_id":48088206016767,"sku":"9781420085594","price":290.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_1e25cc62-bd84-44c1-a44f-07a8422ca57b.jpg?v=1769103640","url":"https:\/\/www.whiterainbookhouse.com\/products\/epilepsy-jong-rho-9781420085594","provider":"WR Book House","version":"1.0","type":"link"}