{"product_id":"genetic-and-epigenetic-regulations-of-bozena-smolkova-9783036571850","title":"Genetic and Epigenetic Regulations of Tumor Progression and Metastasis","description":"\u003cp\u003eGenetic aberrations and epigenetic modifications are critical drivers of cancer progression and metastasis. Although recurrent mutations in primary and metastatic cancers have been shown to be concordant, there are several metastasis-associated mutations responsible for resistance to specific therapies that are frequently located in genes that regulate DNA methylation and chromatin modifications. Recent studies have shown that distinct subgroups of poor-prognosis tumors lack genetic alterations but are epigenetically regulated, pointing to the critical role of epigenetic modifications in cancer progression. This Special Issue provides novel insights into the mechanisms underlying processes associated with cancer cell plasticity and the development of metastatic disease.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Bozena Smolkova\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 303657185X\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9783036571850\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Mdpi AG\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 04\/06\/2023\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 208\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.43lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.61h x 6.69w x 0.69d","brand":"Bozena Smolkova","offers":[{"title":"Hardcover","offer_id":48113797398783,"sku":"9783036571850","price":73.14,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_8a1985dd-327e-4706-97ac-6e9a5a46f6fb.jpg?v=1769617362","url":"https:\/\/www.whiterainbookhouse.com\/products\/genetic-and-epigenetic-regulations-of-bozena-smolkova-9783036571850","provider":"WR Book House","version":"1.0","type":"link"}