{"product_id":"genome-plasticity-in-health-and-diego-a-forero-9780128178195","title":"Genome Plasticity in Health and Disease","description":"\u003cp\u003e\u003ci\u003eGenome Plasticity in Health and Disease \u003c\/i\u003eprovides a fully up-to-date overview on genome plasticity and its role in human physiology and disease. Following an introduction to the field, a diverse range of chapters cover genomic and epigenomic analysis and the use of model organisms and genomic databases in studies. Specific molecular and biochemical mechanisms of genome plasticity are examined, including somatic variants, De Novo variants, founder variations, isolated populations dynamics, copy-number variations, mobile elements, DNA methylation, histone modifications, transcription factors, non-coding RNAs, telomere dynamics and RNA editing. \u003c\/p\u003e \u003cp\u003eLater chapters explore disease relevance for cancer, as well as cardiovascular, neuropsychiatric, inflammatory, and endocrine disease, and associated pathways for drug discovery.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Diego A. Forero\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0128178191\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780128178195\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Academic Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 04\/07\/2020\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 288\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback","brand":"Diego A. Forero","offers":[{"title":"Paperback","offer_id":48112847454463,"sku":"9780128178195","price":175.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_b24f3d56-e5dd-4614-9ff0-d5d69a44f0bd.jpg?v=1769611343","url":"https:\/\/www.whiterainbookhouse.com\/products\/genome-plasticity-in-health-and-diego-a-forero-9780128178195","provider":"WR Book House","version":"1.0","type":"link"}