{"product_id":"genomic-disorders-james-r-lupski-9781617376429","title":"Genomic Disorders: The Genomic Basis of Disease","description":"A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated with disease. Technologies to assay for such structural variation of the human genome and to model genomic disorders in mice are also presented. Two appendices detail the genomic disorders, providing genomic features at the locus undergoing rearrangement, their clinical features, and frequency of detection.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e James R. Lupski\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1617376426\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781617376429\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Humana\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 12\/09\/2010\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 426\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.70lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.00w x 0.91d","brand":"James R. Lupski","offers":[{"title":"Paperback","offer_id":47424447545599,"sku":"9781617376429","price":119.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_59715b73-b3b9-4998-a984-9646204a0694.jpg?v=1761530283","url":"https:\/\/www.whiterainbookhouse.com\/products\/genomic-disorders-james-r-lupski-9781617376429","provider":"WR Book House","version":"1.0","type":"link"}