{"product_id":"glycosylation-engineering-of-biopharmaceuticals-alain-beck-9781627033268","title":"Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols","description":"\u003cp\u003ePart I: Glyco-Engineering of Therapeutic Proteins\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e1. Engineering of Therapeutic and Diagnostic \u003ci\u003eO\u003c\/i\u003e-Glycans on Recombinant Mucin-Type Immunoglobulin Fusion Proteins Expressed in CHO Cells\u003c\/p\u003e\u003cp\u003e Linda Lindberg, Jining Liu, and Jan Holgersson\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e2. Engineering a Human-Like Glycosylation to Produce Therapeutic Glycoproteins Based on 6-Linked Sialylation in CHO Cells\u003c\/p\u003e\u003cp\u003e Nassimal El Maï, Sandrine Donadio-Andréi, Chloé Iss, Valérie Calabro, and Catherine Ronin\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e3. Glycoengineered \u003ci\u003ePichia\u003c\/i\u003e-Based Expression of Monoclonal Antibodies\u003c\/p\u003e\u003cp\u003e Dongxing Zha\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e4. N-Glycosylation Humanization for Production of Therapeutic Recombinant Glycoproteins in Saccharomyces cerevisiae\u003c\/p\u003e\u003cp\u003e Christelle Arico, Christine Bonnet, and Christophe Javaud\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e5. Engineering the Baculovirus Genome to Produce Galactosylated Antibodies in Lepidopteran Cells\u003c\/p\u003e\u003cp\u003e Sylvie Juliant, Marylêne Lévêque, Pierre Cérutti, Annick Ozil, Sylvie Choblet, Marie-Luce Violet, Marie-Christine Slomianny, Anne Harduin-Lepers, and Martine Cérutti\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003ePart II: Glycoanalytics\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e6. Nano LC Chips MS\/MS for the Characterization of N-Glycopeptides Generated from Trypsin Digestion of a Monoclonal Antibody\u003c\/p\u003e\u003cp\u003e Elsa Wagner-Rousset, Christine Schaeffer-Reiss, Audrey Bednarczyk, Nathalie Corvaïa, Alain Van Dorsselaer, and Alain Beck\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e7. Cetuximab Fab and Fc N-Glycan Fast Characterization Using IdeS Digestion and Liquid Chromatography Coupled to Electrospray Ionization Mass Spectrometry\u003c\/p\u003e\u003cp\u003e Marie-Claire Janin-Bussat, Laure Tonini, Céline Huillet, Olivier Colas, Christine Klinguer-Hamour, Nathalie Corvaïa, and Alain Beck\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e8. Therapeutic Antibody Glycosylation Analysis: A Contract Research Organization Perspective in the Frame of Batch Release or Comparability Support\u003c\/p\u003e\u003cp\u003e Arnaud Delobel, Fabrice Cantais, Anicet Catrain, Erell Dereux, and Géry Van Vyncht\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e9. Mass Spectrometric Analysis of \u003ci\u003eO\u003c\/i\u003e-Linked Oligosaccharides from Various Recombinant Expression Systems\u003c\/p\u003e\u003cp\u003e Diarmuid T. Kenny, Stefan Gaunit, Catherine A. Hayes, Anki Gustafsson, Magnus Sjöblom, Jan Holgersson, and Niclas G. Karlsson\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e10. Assessing Fc Glycan Heterogeneity of Therapeutic Recombinant Monoclonal Antibodies Using NP-HPLC\u003c\/p\u003e\u003cp\u003e T. Shantha Raju\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e11. Application of Capillary Electrophoresis in Glycoprotein Analysis\u003c\/p\u003e\u003cp\u003e Richard R. Rustandi, Carrie Anderson, and Melissa Hamm\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e12. Characterization of Glycoprotein Biopharmaceutical Products by Caliper LC90 CE-SDS Gel Technology\u003c\/p\u003e\u003cp\u003e Grace Chen, Sha Ha, and Richard R. Rustandi\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e13. Hydrophobic Interaction Chromatography to Analyze Glycoproteins\u003c\/p\u003e\u003cp\u003e Richard R. Rustandi\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e14. Lectin Glycoprofiling of Recombinant Therapeutic Interleukin-7\u003c\/p\u003e\u003cp\u003e Ludovic Landemarre and Eric Duverger\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e15. Analysis of Monoclonal Antibodies by Sedimentation Velocity Analytical Ultracentrifugation\u003c\/p\u003e\u003cp\u003e W. Blaine Stine, Jr.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003ePart III: Glycoprotein Complexes Characterization\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e16. Noncovalent Mass Spectrometry for the Characterization of Antibody\/Antigen Complexes\u003c\/p\u003e\u003cp\u003e Cédric Atmanene, Elsa Wagner-Rousset, Nathalie Corvaïa, Alain Van Dorsselaer, Alain Beck, and Sarah Sanglier-Cianferani\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e17. Conformational Analysis of Recombinant Monoclonal Antibodies with Hydrogen\/Deuterium Exchange Mass Spectrometry\u003c\/p\u003e\u003cp\u003e Damian Houde and John R. Engen\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e18. Epitope Mapping of Antibodies by Mass Spectroscopy: A Case Study\u003c\/p\u003e\u003cp\u003e Victor H. Obungu, Valentina Gelfanova, and Lihua Huang\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003ePart IV: PK\/PD Assays for Therapeutic Antibodies\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e19. Evaluation of Antibody-Dependent Cell Cytotoxicity Using Lactate Des\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Alain Beck\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1627033262\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781627033268\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Humana\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 03\/09\/2013\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 355\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.87lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.28h x 7.18w x 1.00d\u003c\/p\u003e","brand":"Alain Beck","offers":[{"title":"Hardcover","offer_id":44067885482239,"sku":"9781627033268","price":199.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_2e291bab-c8cf-4fbd-95db-a2b7ae2b9a60.jpg?v=1685415837","url":"https:\/\/www.whiterainbookhouse.com\/products\/glycosylation-engineering-of-biopharmaceuticals-alain-beck-9781627033268","provider":"WR Book House","version":"1.0","type":"link"}