{"product_id":"herbal-treatment-of-major-depression-scott-mendelson-9781032087153","title":"Herbal Treatment of Major Depression: Scientific Basis and Practical Use","description":"\u003cp\u003eThis unique volume presents new understandings of the neurochemical nature of major depression, and how herbs and their constituent flavonoids and terpenes appear to address some of the mechanisms now thought to be involved. It explores how recent studies of the rapid antidepressant effects of ketamine inform neuroscientists about deep intracellular mechanisms of antidepressant action that have little to do with simple enhancement of monoaminergic activity. These mechanisms include actions on PI3K, Akt, mTOR, GSK3, BDNF, and other intracellular pathways. New theories of the pathophysiology underlying major depression, such as oxidative damage, inflammation, stress and insulin resistance are then explored.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003eKey Features: \u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cul\u003e\n\u003cbr\u003e\u003cbr\u003e\u003cli\u003eFocuses on oxidative damage, inflammation, and metabolic syndrome. \u003c\/li\u003e\n\u003cbr\u003e\u003cbr\u003e\u003cli\u003eExplains that a significant percentage of people treated for major depression obtain little if any relief from standard antidepressant medications. \u003c\/li\u003e\n\u003cbr\u003e\u003cbr\u003e\u003cli\u003eThese facts lead to discussion of herbs that can be used to treat major depression, as well as consideration of the scientific basis for how these herbs act. \u003c\/li\u003e\n\u003cbr\u003e\u003cbr\u003e\u003cli\u003eThe antidepressant properties of 66 herbs are discussed, along with dosing and safety information.\u003c\/li\u003e\n\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Scott D. Mendelson\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1032087153\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781032087153\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e CRC Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 06\/30\/2021\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 448\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.45lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.20h x 6.10w x 1.00d\u003c\/ul\u003e","brand":"Scott D. Mendelson","offers":[{"title":"Paperback","offer_id":43944736325887,"sku":"9781032087153","price":59.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/products\/img_cac0e449-d699-45e7-9ceb-69003e6d6994.jpg?v=1681504892","url":"https:\/\/www.whiterainbookhouse.com\/products\/herbal-treatment-of-major-depression-scott-mendelson-9781032087153","provider":"WR Book House","version":"1.0","type":"link"}