{"product_id":"histone-methyltransferases-raphal-margueron-9781071624807","title":"Histone Methyltransferases: Methods and Protocols","description":"\u003cp\u003eThis volume provides methods used to investigate histone methyltransferase function. Chapters guide readers through a comprehensive set of approaches that detail phylogenetic diversity, histone demethylase activities \u003ci\u003ein vitro, \u003c\/i\u003e generating chromatin substrates, auto-methylation, quantification of metabolites, protein purification, crystallization, X-ray structure, cryogenic electron microscopy, assessing genome-wide patterns, CUT\u0026amp;Tag in mouse embryonic tissues, chemical biology approaches, peptide SPOT arrays, nascent chromatin capture, ectopic protein tethering, computational models, and development of methyltransferase inhibitors. Written in the format of the highly successful \u003ci\u003eMethods in Molecular Biology \u003c\/i\u003eseries, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003eAuthoritative and cutting-edge, \u003ci\u003eHistone Methyltransferases: Methods and Protocols \u003c\/i\u003eaims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Rapha? Margueron\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1071624806\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781071624807\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Humana\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 06\/24\/2022\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 495\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 2.44lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.00w x 1.13d","brand":"Rapha? Margueron","offers":[{"title":"Hardcover","offer_id":44123311997183,"sku":"9781071624807","price":249.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_f11a5272-a1ba-4028-8a59-de8e79e952d6.jpg?v=1687430164","url":"https:\/\/www.whiterainbookhouse.com\/products\/histone-methyltransferases-raphal-margueron-9781071624807","provider":"WR Book House","version":"1.0","type":"link"}