{"product_id":"individual-participant-data-meta-analysis-richard-d-riley-9781119333722","title":"Individual Participant Data Meta-Analysis: A Handbook for Healthcare Research","description":"\u003cp\u003e\u003ci\u003eIndividual Participant Data Meta-Analysis: A Handbook for Healthcare Research\u003c\/i\u003e provides a comprehensive introduction to the fundamental principles and methods that healthcare researchers need when considering, conducting or using individual participant data (IPD) meta-analysis projects. Written and edited by researchers with substantial experience in the field, the book details key concepts and practical guidance for each stage of an IPD meta-analysis project, alongside illustrated examples and summary learning points.\u003c\/p\u003e \u003cp\u003eSplit into five parts, the book chapters take the reader through the journey from initiating and planning IPD projects to obtaining, checking, and meta-analysing IPD, and appraising and reporting findings. The book initially focuses on the synthesis of IPD from randomised trials to evaluate treatment effects, including the evaluation of participant-level effect modifiers (treatment-covariate interactions). Detailed extension is then made to specialist topics such as diagnostic test accuracy, prognostic factors, risk prediction models, and advanced statistical topics such as multivariate and network meta-analysis, power calculations, and missing data.\u003c\/p\u003e \u003cp\u003eIntended for a broad audience, the book will enable the reader to: \u003c\/p\u003e \u003cul\u003e \u003cli\u003eUnderstand the advantages of the IPD approach and decide when it is needed over a conventional systematic review\u003c\/li\u003e \u003cli\u003eRecognise the scope, resources and challenges of IPD meta-analysis projects\u003c\/li\u003e \u003cli\u003eAppreciate the importance of a multi-disciplinary project team and close collaboration with the original study investigators\u003c\/li\u003e \u003cli\u003eUnderstand how to obtain, check, manage and harmonise IPD from multiple studies\u003c\/li\u003e \u003cli\u003eExamine risk of bias (quality) of IPD and minimise potential biases throughout the project\u003c\/li\u003e \u003cli\u003eUnderstand fundamental statistical methods for IPD meta-analysis, including two-stage and one-stage approaches (and their differences), and statistical software to implement them\u003c\/li\u003e \u003cli\u003eClearly report and disseminate IPD meta-analyses to inform policy, practice and future research\u003c\/li\u003e \u003cli\u003eCritically appraise existing IPD meta-analysis projects\u003c\/li\u003e \u003cli\u003eAddress specialist topics such as effect modification, multiple correlated outcomes, multiple treatment comparisons, non-linear relationships, test accuracy at multiple thresholds, multiple imputation, and developing and validating clinical prediction models\u003c\/li\u003e \u003c\/ul\u003e Detailed examples and case studies are provided throughout.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Richard D. Riley\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1119333725\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781119333722\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Wiley\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 06\/08\/2021\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 560\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 2.95lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.10h x 7.20w x 1.10d","brand":"Richard D. Riley","offers":[{"title":"Hardcover","offer_id":43993486360831,"sku":"9781119333722","price":96.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_f3206929-c258-45c8-b3e8-f472f0c45fea.jpg?v=1683324603","url":"https:\/\/www.whiterainbookhouse.com\/products\/individual-participant-data-meta-analysis-richard-d-riley-9781119333722","provider":"WR Book House","version":"1.0","type":"link"}