{"product_id":"indwelling-neural-implants-william-m-reichert-9780367387938","title":"Indwelling Neural Implants: Strategies for Contending with the in Vivo Environment","description":"\u003cp\u003eDespite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. \u003cbr\u003eOffering contributions from pioneering researchers in neuroprosthetics and tissue repair, \u003cb\u003eIndwelling Neural Implants: Strategies for Contending with the \u003ci\u003eIn Vivo\u003c\/i\u003e Environment\u003c\/b\u003e examines many of these challenges, paying particular attention to how the healing of tissues surrounding an implant can impact the intended use of a device. The contributions are divided into four sections \u003cbr\u003e- Part one examines wound healing from the initial insertion trauma through the inflammatory and repair process, explaining how the action of healing varies throughout different areas of the body. \u003cbr\u003e- Part two considers various performance issues specific to particular implant components, including those that arise from the chemical, mechanical, thermal, and electrical impact on surrounding tissues. It discusses challenges that result from chronic tissue stimulation and heat effects that occur with on-chip and telemetric processing. \u003cbr\u003e- Part three presents both \u003ci\u003ein vitro \u003c\/i\u003eand \u003ci\u003ein vivo\u003c\/i\u003e approaches to assessing wound healing response to materials. It includes the contribution of the developer of a chronic hollow fiber membrane implant who explains how an \u003ci\u003ein vivo\u003c\/i\u003e model is used to assess molecular transport in brain tissue surrounding the implant. \u003cbr\u003e- The final section evaluates molecular and materials strategies for intervening in CNS wound repair and enhancing the electrical communication between the electrode surface and the surrounding tissue. It also presents novel approaches to nerve regeneration and repair.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e William M. Reichert\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 036738793X\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780367387938\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e CRC Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 10\/23\/2019\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 296\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.40lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.20h x 6.10w x 0.50d","brand":"William M. Reichert","offers":[{"title":"Paperback","offer_id":48447722160383,"sku":"9780367387938","price":89.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_891bd758-550d-4c00-8499-b28d61ed5aed.jpg?v=1777234367","url":"https:\/\/www.whiterainbookhouse.com\/products\/indwelling-neural-implants-william-m-reichert-9780367387938","provider":"WR Book House","version":"1.0","type":"link"}