{"product_id":"ipscs-for-modeling-central-nervous-alexander-birbrair-9780323857642","title":"Ipscs for Modeling Central Nervous System Disorders, Volume 6","description":"The series \u003ci\u003eAdvances in Stem Cell Biology\u003c\/i\u003e is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. \u003cp\u003e\u003c\/p\u003e\u003ci\u003eiPSCs for Modeling Central Nervous System Disorders, Volume 6\u003c\/i\u003e addresses how induced pluripotent stem cells can be used to model various CNS disorders. \u003cp\u003e\u003c\/p\u003eSomatic cells can be reprogrammed into Induced pluripotent stem cells by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. The volume teaches readers about current advances in the field. This book describes the use of induced pluripotent stem cells to model several CNS diseases in vitro, enabling us to study the cellular and molecular mechanisms involved in different CNS pathologies. Further insights into these mechanisms will have important implications for our understanding of CNS disease appearance, development, and progression. In recent years, remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cell types, tissues and organs using state-of-art techniques. These advantages facilitated identification of key targets and definition of the molecular basis of several CNS disorders. This volume will cover what we know so far about the use of iPSCs to model different CNS disorders, such as: Alzheimer's disease, Autism, Amyotrophic Lateral Sclerosis, Schizophrenia, Fragile X Syndrome, Spinal Muscular Atrophy, Rett Syndrome, Angelman syndrome, Parkinson s Disease, Leber Hereditary Optic Neuropathy, Anorexia Nervosa, and more. \u003cp\u003e\u003c\/p\u003eThe volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and neuroscience; and is contributed by world-renowned authors in the field. \u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Alexander Birbrair\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0323857647\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780323857642\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Academic Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 04\/30\/2021\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 352\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback","brand":"Alexander Birbrair","offers":[{"title":"Paperback","offer_id":48587617501439,"sku":"9780323857642","price":175.0,"currency_code":"USD","in_stock":false}],"url":"https:\/\/www.whiterainbookhouse.com\/products\/ipscs-for-modeling-central-nervous-alexander-birbrair-9780323857642","provider":"WR Book House","version":"1.0","type":"link"}