{"product_id":"label-free-technologies-for-drug-discovery-matthew-cooper-9780470746837","title":"Label-Free Technologies for Drug Discovery","description":"Over the past two decades the benefits of label-free biosensor analysis have begun to make an impact in the market, and systems are beginning to be used as mainstream research tools in many drug discovery laboratories. \u003cp\u003e\u003ci\u003eLabel-Free Technologies For Drug Discovery\u003c\/i\u003e summarises the latest and emerging developments in label-free detection systems, their underlying technology principles and end-user case studies that reveal the power and limitations of label-free in all areas of drug discovery.\u003c\/p\u003e \u003cp\u003eLabel-free technologies discussed include SPR, NMR, high-throughput mass spectrometry, resonant waveguide plate-based screening, transmitted-light imaging, isothermal titration calorimetry, optical and impedance cell-based assays and other biophysical methods. The technologies are discussed in relation to their use as screening technologies, high-content technologies, hit finding and hit validation strategies, mode of action and ADME\/T, access to difficult target classes, cell-based receptor\/ligand interactions particularly orphan receptors, and antibody and small molecule affinity and kinetic analysis.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eLabel-Free Technologies For Drug Discovery\u003c\/i\u003e is an essential guide to this emerging class of tools for researchers in drug discovery and development, particularly high-throughput screening and compound profiling teams, medicinal chemists, structural biologists, assay developers, ADME\/T specialists, and others interested in biomolecular interaction analysis.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Matthew Cooper\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0470746831\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780470746837\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Wiley\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 03\/14\/2011\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 352\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.40lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.00h x 6.00w x 0.81d\u003cbr\u003e\u003cbr\u003e\u003cb\u003eReview Citation(s): \u003c\/b\u003e\u003cbr\u003e\u003ci\u003eReference and Research Bk News\u003c\/i\u003e 06\/01\/2011 pg. 276","brand":"Matthew Cooper","offers":[{"title":"Hardcover","offer_id":48013747749119,"sku":"9780470746837","price":169.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_e90826d2-2b3f-4872-888d-10c38f5e6ab5.jpg?v=1767744518","url":"https:\/\/www.whiterainbookhouse.com\/products\/label-free-technologies-for-drug-discovery-matthew-cooper-9780470746837","provider":"WR Book House","version":"1.0","type":"link"}