{"product_id":"leishmania-subrata-adak-9781908230522","title":"Leishmania: Current Biology and Control","description":"Every year, with an estimated 1.3 million new cases and more than 20,000 deaths, Leishmaniasis continues to be a menace in countries across the globe. With the absence of an anti-Leishmania vaccine - along with the toxicity of current anti-parasite drugs and coupled with the rapid emergence of drug resistant Leishmania strains - there remains significant challenges for disease control. This has spurred a plethora of research initiatives into parasite biology, parasite-host interaction, mechanisms of disease pathogenesis, drug development, and the molecular mechanism of drug resistance. Insights obtained from various studies are essential for the development of novel anti-Leishmania treatment strategies. In this timely book, respected Leishmania experts distil important current research, highlighting the most insightful discoveries in the field. Topics covered include: modulation of host miRNA * heat shock proteins * iron in the Leishmania-macrophage interaction * oxidative and nitrosative stress response * cell death * strategies for immune evasion * STAT signaling * parasite modulation of toll-like receptors in macrophages * T cells in Leishmania infection * vaccine biology * inhibitors of Leishmania DNA topoisomerases * mechanism of drug resistance in visceral Leishmaniasis. The book is an essential text for everyone in the Leishmania community and is recommended for researchers working in related fields.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Subrata Adak\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1908230525\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781908230522\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Caister Academic Press Limited\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 01\/01\/2015\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 254\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.66lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.61h x 6.69w x 0.81d","brand":"Subrata Adak","offers":[{"title":"Hardcover","offer_id":48014075592959,"sku":"9781908230522","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_9e1e89c2-a929-417d-86b0-55c05abd4df1.jpg?v=1767746570","url":"https:\/\/www.whiterainbookhouse.com\/products\/leishmania-subrata-adak-9781908230522","provider":"WR Book House","version":"1.0","type":"link"}