{"product_id":"leukocyte-recruitment-endothelial-cell-adhesion-tucker-collins-9781461356172","title":"Leukocyte Recruitment, Endothelial Cell Adhesion Molecules, and Transcriptional Control: Insights for Drug Discovery","description":"The localized attachment of circulating leukocytes to endothelium has been recognized as the cellular hallmark of the inflammatory response. This adhesive interaction, a necessary antecedent to the emigration of leukocytes from the blood into the tissues, is mediated by vascular adhesion molecules. \u003cem\u003eLeukocyte Recruitment, Endothelial Cell Adhesion\u003c\/em\u003e \u003cem\u003eMolecules and Transcriptional Control: Insights for Drug Discovery\u003c\/em\u003e outlines some of the cellular and molecular mechanisms of inflammation with contributions from top researchers.\u003cbr\u003e This volume provides an overview of three of these endothelial adhesion molecules, as examples of key mediators of leukocyte recruitment. It reviews the structure and regulation of these cell surface proteins and focus on the rapidly expanding field of transcriptional regulation of these inducible proteins, and closes with a discussion of drug discovery possibilities that target the regulation of leukocyte recruitment. \u003cbr\u003e This book will be of interest for any researchers, in academia or industry, looking for an overview of leukocyte recruitment or novel approaches to drug discovery.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Tucker Collins\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1461356172\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781461356172\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Springer\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 11\/05\/2012\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 327\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.06lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.21h x 6.14w x 0.72d","brand":"Tucker Collins","offers":[{"title":"Paperback","offer_id":47930799653119,"sku":"9781461356172","price":169.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_68313e30-e36a-4999-9dfe-f075fb5cf2d8.jpg?v=1766344353","url":"https:\/\/www.whiterainbookhouse.com\/products\/leukocyte-recruitment-endothelial-cell-adhesion-tucker-collins-9781461356172","provider":"WR Book House","version":"1.0","type":"link"}