{"product_id":"mass-spectrometry-based-chemical-proteomics-w-andy-tao-9781118969557","title":"Mass Spectrometry-Based Chemical Proteomics","description":"\u003cp\u003e\u003cb\u003ePROVIDES STRATEGIES AND CONCEPTS FOR UNDERSTANDING CHEMICAL PROTEOMICS, AND ANALYZING PROTEIN FUNCTIONS, MODIFICATIONS, AND INTERACTIONS--EMPHASIZING MASS SPECTROMETRY THROUGHOUT\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eCovering mass spectrometry for chemical proteomics, this book helps readers understand analytical strategies behind protein functions, their modifications and interactions, and applications in drug discovery. It provides a basic overview and presents concepts in chemical proteomics through three angles: Strategies, Technical Advances, and Applications. Chapters cover those many technical advances and applications in drug discovery, from target identification to validation and potential treatments.\u003c\/p\u003e \u003cp\u003eThe first section of \u003ci\u003eMass Spectrometry-Based Chemical Proteomics\u003c\/i\u003e starts by reviewing basic methods and recent advances in mass spectrometry for proteomics, including shotgun proteomics, quantitative proteomics, and data analyses. The next section covers a variety of techniques and strategies coupling chemical probes to MS-based proteomics to provide functional insights into the proteome. In the last section, it focuses on using chemical strategies to study protein post-translational modifications and high-order structures.\u003c\/p\u003e \u003cul\u003e \u003cli\u003eSummarizes chemical proteomics, up-to-date concepts, analysis, and target validation\u003c\/li\u003e \u003cli\u003eCovers fundamentals and strategies, including the profiling of enzyme activities and protein-drug interactions\u003c\/li\u003e \u003cli\u003eExplains technical advances in the field and describes on shotgun proteomics, quantitative proteomics, and corresponding methods of software and database usage for proteomics\u003c\/li\u003e \u003cli\u003eIncludes a wide variety of applications in drug discovery, from kinase inhibitors and intracellular drug targets to the chemoproteomics analysis of natural products\u003c\/li\u003e \u003cli\u003eAddresses an important tool in small molecule drug discovery, appealing to both academia and the pharmaceutical industry\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eMass Spectrometry-Based Chemical Proteomics\u003c\/i\u003e is an excellent source of information for readers in both academia and industry in a variety of fields, including pharmaceutical sciences, drug discovery, molecular biology, bioinformatics, and analytical sciences.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e W. Andy Tao\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1118969553\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781118969557\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Wiley\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 09\/04\/2019\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 448\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.85lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.10h x 6.00w x 1.00d","brand":"W. Andy Tao","offers":[{"title":"Hardcover","offer_id":44055961501951,"sku":"9781118969557","price":188.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_05776a56-9451-4d44-a4e4-e11c2bd0c5a1.jpg?v=1685038764","url":"https:\/\/www.whiterainbookhouse.com\/products\/mass-spectrometry-based-chemical-proteomics-w-andy-tao-9781118969557","provider":"WR Book House","version":"1.0","type":"link"}