{"product_id":"mechanisms-of-cell-death-and-benjamin-dehay-9780323899437","title":"Mechanisms of Cell Death and Approaches to Neuroprotection\/Disease Modification in Parkinson's Disease: Volume 2","description":"\u003cp\u003e\u003ci\u003eMechanisms of Cell Death and Approaches to Neuroprotection\/Disease Modification in Parkinson's Disease\u003c\/i\u003e explores the results of numerous studies surrounding in vitro and animal model evidence that looks at the impact of a-synucleinopathy on neuronal dysfunction and behavioral impairments, (ii) how research in animal models supports the development of therapeutic strategies, and (iii) how findings in animal models might relate to the disease process in humans. In this book, the author's shed light upon the complex scenario of the mechanisms of cell death and approaches to neuroprotection\/disease modification in PD, both in vitro to in vivo.\u003c\/p\u003e \u003cp\u003eAlong with degeneration, the pathological hallmark of PD is the presence of intraneuronal proteinaceous cytoplasmic inclusions, named Lewy Bodies (LB) that invade the whole nervous system as the disease progresses. Several fundamental discoveries have shed light upon the implication of the a-syn protein in the pathogenesis of familial and sporadic forms of PD. Other proteins also accumulate in LB, but a-syn is a major protein component of the pathological landmarks.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Benjamin Dehay\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0323899439\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780323899437\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Academic Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 11\/12\/2021\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 314\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.30lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.00h x 6.00w x 0.75d","brand":"Benjamin Dehay","offers":[{"title":"Hardcover","offer_id":44169971663103,"sku":"9780323899437","price":220.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_8feb5cdd-9950-49e9-9e99-cdf0a857092c.jpg?v=1689656058","url":"https:\/\/www.whiterainbookhouse.com\/products\/mechanisms-of-cell-death-and-benjamin-dehay-9780323899437","provider":"WR Book House","version":"1.0","type":"link"}