{"product_id":"mechanisms-of-lymphocyte-activation-and-international-conference-on-lymphocyte-a-9780306443121","title":"Mechanisms of Lymphocyte Activation and Immune Regulation IV: Cellular Communications","description":"Section I: T Cell Receptors and T Cell Activation.- T Cell Receptor Structure and Function: Analysis by Expression of Portions of Isolated Subunits.- The T Cell Antigen Receptor Tyrosine Kinase Pathway.- Dissection of the Hb(64-76) Determinant Reveals That the T Cell Receptor May Have the Capacity to Differentially Signal.- CD28 Receptor Crosslinking Induces Tyrosine Phosphorylation of PLC?1.- Structure and Function of CD45: A Leukocyte-Specific Protein Tyrosine Phosphatase.- Multidrug Resistant Gene 1 Product in Human T Cell Subsets: Role of Protein Kinase C Isoforms and Regulation by Cyclosporin A.- Integrins, T Cells, and Autoimmunity.- The Interleukin-2 Receptor: A Target for Immunotherapy.- Section II: T Cell Development.- Lymphocyte Development in Mice Deficient for MHC Class I Expression.- Generation of Mutant Mice Lacking Surface Expression of CD4 or CD8 Gene Targeting.- Alteration of T Cell Lineage Commitment by Expression of a Hybrid CD8\/CD4 Transgene.- Differential Involvement of Protein Tyrosine Kinases p56lck and p59fyn in T Cell Development.- Mechanism of Tolerance Induction.- Section III: B Cell Development, Activation, Proliferation, And Differentiation.- B-Lymphocyte Lineage-Committed, IL-7 and Stroma Cell-Reactive Progenitors and Precursors, and Their Differentiation to B Cells.- Regulatory Cells and Cytokines Involved in Primary B Lymphocyte Production.- The Role of IL-7 and Its Receptor in B-Cell Ontogeny.- Role of Contact and Soluble Factors in the Growth and Differentiation of B Cells by Helper T Cell.- B-Cell Activation Mediated by Interactions with Membranes from Helper T Cells.- The Low Affinity IgE Fc Receptor (CD23) Participates in B Cell Activation.- Section IV: Adhesion Molecules: Structure, Regulation and Functions.- T Cell Adhesion Cascades: General Considerations and Illustration with CD31.- Analyses of VLA-4 Structure and Function.- On the Regulation of ?2 Integrins.- Leukocyte-Endothelial Cell Adhesion as an Active, Multi-Step Process: A Combinatorial Mechanism for Specificity and Diversity in Leukocyte Targeting.- Contributors.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e International Conference on Lymphocyte A\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0306443120\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780306443121\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Plenum Publishing Corporation\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 11\/30\/1992\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 220\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.22lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.61h x 6.69w x 0.56d","brand":"International Conference on Lymphocyte A","offers":[{"title":"Hardcover","offer_id":47420907323647,"sku":"9780306443121","price":99.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_39dea30c-7783-4f31-8d24-ad0cf5c06cef.jpg?v=1761526464","url":"https:\/\/www.whiterainbookhouse.com\/products\/mechanisms-of-lymphocyte-activation-and-international-conference-on-lymphocyte-a-9780306443121","provider":"WR Book House","version":"1.0","type":"link"}